Results 141 to 150 of about 6,042,835 (382)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Special Libraries, February 1962 [PDF]

open access: yes, 1962
Volume 53, Issue 2https://scholarworks.sjsu.edu/sla_sl_1962/1001/thumbnail ...
Special Libraries Association
core   +2 more sources

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

An Analysis of the Match between the Forms and Vocabulary of Users\\\' Subject Queries with the Persian Subject Headings in a University OPAC

open access: yesIranian Journal of Information Processing & Management, 2012
This research aimed to compare the degree of form and vocabulary match between user's subject queries (user vocabulary) and the List of Persian subject headings (system vocabulary) in two subject areas: 1) Agriculture (applied sciences); 2) library and ...
Rahmatollah Fattahi, Amir Nikzaman
doaj  

Of subject documents on education, pedagogy, psychology [PDF]

open access: yes
У посібнику висвітлено основні питання теорії й загальної методики предметизації, зокрема: теоретичні основи предметизації, документ як об’єкт предметизації, предметизація як метод аналітико-синтетичного опрацювання документів, основні прийоми загальної ...
Зоріна, Наталія Євгенівна   +1 more
core  

Search Process Checklist [PDF]

open access: yes, 2018
The Search Process Checklist is a tool that is used in instructional sessions with nurses in reference to evidence-based practice and literature searching. It is intended as a reference handout. It is under a creative commons license. If you would like a
Brown, Roy E.
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

About the MeSH information and retrieval query language in the area of activity of Polish academic libraries of medical universities

open access: yesForum Bibliotek Medycznych
The article presents the history of MeSH, the information and retrieval query language in Poland, in the context of cooperation between academic medical libraries. It also discusses the role of the Central Medical Library in the implementation of medical
Magdalena Kotlarek-Naskręt
doaj   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

open access: yesAging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst   +4 more
wiley   +1 more source

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