Results 41 to 50 of about 400,752 (311)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Lista de encabezamientos de materia de la Biblioteca del Congreso de los Estados Unidos características generales [PDF]

open access: yes, 2005
The article describes the historical aspects and principles of the Library of Congress Subject Headings (LCSH). It shows their several formats and features adopted by their subject headings, its several subdivisions and syndetic structure.
Cravero, Celso   +2 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Statistical Study on Persian Subject Headings Development

open access: yesInternational Journal of Information Science and Management, 2012
Controlled vocabularies have been frequently used in information retrieval systems. Control of the vocabularies and evaluating the utility of their terms are two critical questions.
M. Tavakolizadeh Ravari
doaj  

Theology, Race and Libraries [PDF]

open access: yes, 2016
Recent theological research into the origin of race and the presence of structural racism in library systems of knowledge organization will be presented.
Coleman, Anita
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Assignment or Selection: Evaluation of Two Different Methods Used During Scientific Research Skill Development for First-Semester Medical Students

open access: yesMedEdPORTAL, 2016
Introduction As part of the scientific research skill development for first-semester medical students, we evaluated two different methods employed during a novel activity based on Medical Subject Heading (MeSH) terms. This module (called the Miniproject)
Jennifer Protudjer, Amelie Plymoth
doaj   +1 more source

Use of the LCSH System: Realities [PDF]

open access: yes, 1996
This study examines the question of whether academic libraries keep up with changes in the Library of Congress subject heading system. An analysis of the handling of 15 subject headings in 50 academic library catalogs available online through the ...
Connell, Tschera Harkness
core  

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