Results 81 to 90 of about 205,338 (288)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Asiasana hallussa? – Opiskelijoiden tiedonhakukäyttäytyminen ja asiasanat osana sitä

Informaatiotutkimus, 2017
The study focuses on the information seeking behaviour of graduate students and the role of subject headings in it. The aim of the study was to see if students are aware of indexing.
Hilda Ruokolainen
doaj   +1 more source

Chapter 2 - A Discussion of Methods, pp. 31-44 [PDF]

, 1944
The Catherwood Library and ILR School at Cornell are pleased to again make available an extremely important index of major labor union publications, long out of print. It is Lloyd G. Reynolds and Charles C.
Killingsworth, Charles C, Reynolds, Lloyd G   +1 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Avaliação da eficácia de recuperação do sistema de indexação PRECIS

Ciência da Informação, 1989
A importância do índice de assunto, enquanto sistema de recuperação da informação, em uma biblioteca ou centro de informação. Influência do método de indexação na constituição de índices de assunto.
Mariângela Spotti Lopes Fujita
doaj  

DESCRITORES EM CIÊNCIAS DA SAÚDE NAS TESES E DISSERTAÇÕES DE MESTRADO, NA ÁREA DE DOENÇAS RESPIRATÓRIAS

Acta Cirúrgica Brasileira, 1999
O processo de indexação consiste em duas fases: primeira, identificar e representar o conteúdo intelectual de um documento; segunda, traduzir a análise do assunto para uma linguagem específica, utilizando descritores.
Patrícia Rosas, Carlos Alberto Guimarães, Luiz Felippe Júdice, Carlos Alberto de Castro Ferreira, Else Benetti Marques Válio   +4 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Challenges in AI: Indexing LGBTQ+ fiction

Digital Humanities in the Nordic and Baltic Countries Publications
Efforts to automate cataloging in libraries have progressed significantly, with AI tools like ChatGPT emerging as potential aids. However, automating the subject indexing of LGBTQ+ fiction poses unique challenges.
Koraljka Golub
doaj   +1 more source

Special Libraries, December 1961 [PDF]

, 1960
Volume 52, Issue 10https://scholarworks.sjsu.edu/sla_sl_1961/1009/thumbnail ...
Special Libraries Association
core   +3 more sources