Results 121 to 130 of about 6,560,569 (228)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Police Use of Force with the Mentally ill
, 2016 Police officers experience many difficult situations in their line of duty, but two situations stand out as particularly unsettling for police officers: when they interact with people who are (a) under the influence of drugs or alcohol, and when (b ...
Moore, Chelsea
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Subject position of the child in overcoming learning difficulties (case study)
Консультативная психология и психотерапия, 2012 This paper describes a case of providing psychological and educational assistance a student with mental retardation in overcom-ing learning difficulties.
Zaretsky Yu.V., Zaretsky V.K.
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Immigrant Students at School in Spain: Constructing a Subject of Study
Dve Domovini, 2015 This article discusses the various contexts of the public education of immigrant students in Spain, bringing together the relevant body of literature from more than ten years of research.
Francisco Javier García Castaño +2 more
doaj
Comparing two experimental designs for the study of subject islands in Spanish
IsoglossThis paper investigates the phenomenon of subject islands in Spanish through the lens of two experimental designs, which we refer to as the subject/object design and the simple/complex subject design.
Laura Stigliano +2 more
doaj +1 more source
Chromosome Studies in Agammaglobulinaemic Subjects [PDF]
BMJ, 1965 Y R, AHUJA, H, FUDENBERG
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source