Results 41 to 50 of about 26,506 (286)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Forms of subjectivation : Generation Y and the contemporaneity [PDF]

open access: yes, 2016
This empirical article is a result of a qualitative, exploratory and cross-sectional research in which we investigate the forms of subjectivation of the young people of Generation Y.
Lisboa, Carolina, Verzoni, André
core   +4 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Engineering Entrepreneurial Ethics: Islam after Development in Indonesia

open access: yesMoussons, 2013
This article analyzes a socio-technical scheme to engineer an ethics of entrepreneurship grounded in Islam in contemporary Indonesia. In analyzing these efforts to develop faith, this paper argues that a new form of Islamic practice is being introduced ...
Daromir  Rudnyckyj
doaj   +1 more source

Herman Bavinck and same-sex marriage: A current application of older theological concepts

open access: yesIn die Skriflig, 2023
It seems like an anachronism to turn to Herman Bavinck for a vision of homosexual relationships in the church. It is indeed an anachronism when we look at Bavinck’s treatment of this phenomenon.
Willem van Vlastuin
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

open access: yesAging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst   +4 more
wiley   +1 more source

Les aléas de la subjectivité sous le sémiocapitalisme : Félix Guattari et le potentiel politique des hybrides humains-machines

open access: yesCygne Noir, 2019
Félix Guattari a développé une approche sémiotique mettant en évidence l’idée suivant laquelle le capitalisme usine des subjectivités spécifiques aux différents âges de la vie.
Gary Genosko
doaj  

La promesse du bonheur : introduction

open access: yesGenre, Sexualité et Société, 2015
The work of the queer phenomenologist Sara Ahmed questions the injunctions and identifications produced by affects in order to consider the critical power of feminist, queer and black movements.
Sara Ahmed
doaj   +1 more source

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