Results 131 to 140 of about 13,052,428 (347)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
ANTI-CORRUPTION POLICY IN THE SYSTEM OF LEGAL MEASURES
Russian Journal of Economics and Law, 2015 Objective: to determine the scientific-methodological foundations of anti-corruption policy. Methods: dialectical approach to cognition of social phenomena allows to explore the combination of objective and subjective factors influencing the formation ...
T. V. Filonenko, Y. V. Gayvoronskaya
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Administrative legal relations with the participation of the State Bureau of Investigation
Bulletin of Kharkiv National University of Internal AffairsThe essence, characteristics, and types of administrative legal relations involving the State Bureau of Investigations have been identified. Additionally, suggestions and recommendations for improving the legal foundations of these relations have been ...
А. Т. Komziuk, Ye. А. Lypii
doaj +1 more source
A study of the effectiveness of various methods of muscular relaxation : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]
, 1979 This study was designed to compare the effectiveness of four different methods of skeletal muscle relaxation. Twenty four male, undergraduate student volunteers were recruited for this study, the age range was 18 to 31 years. The Experiment was conducted
Petersen, Daphne Elaine Leslie
core
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Ars PharmaceuticaObjetivos: Durante los últimos años, los profesores del Departamento de Farmacología, Toxicología y Química Terapéutica hemos puesto en marcha un conjunto de acciones docentes con el objetivo de promover en los alumnos del grado de Farmacia la mejora de ...
Miguel Rodamilans +5 more
doaj +1 more source
Effects of bariatric surgery on mortality in Swedish obese subjects.
New England Journal of Medicine, 2007 L. Sjöström +22 more
semanticscholar +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source