Results 91 to 100 of about 34,639 (304)

A Rho Kinase (ROCK) Inhibitor, Y-27632, Inhibits the Dissociation-Induced Cell Death of Salivary Gland Stem Cells

open access: yesMolecules, 2021
Salivary gland stem cells (SGSCs) are potential cell sources for the treatment of salivary gland diseases. The control of cell survival is an essential factor for applying stem cells to regenerative medicine or stem cell-based research.
Kichul Kim   +4 more
doaj   +1 more source

TA-Net: Topology-Aware Network for Gland Segmentation [PDF]

open access: yesarXiv, 2021
Gland segmentation is a critical step to quantitatively assess the morphology of glands in histopathology image analysis. However, it is challenging to separate densely clustered glands accurately. Existing deep learning-based approaches attempted to use contour-based techniques to alleviate this issue but only achieved limited success. To address this
arxiv  

A phenomap of TTR amyloidosis to aid diagnostic screening

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos   +4 more
wiley   +1 more source

Patience Pays Off: A Case of Self Exfoliation of Large Parotid Sialolith [PDF]

open access: yesJournal of Krishna Institute of Medical Sciences University, 2019
Sialolithiasis is one of the common diseases affecting the salivary glands. The submandibular gland is the most commonly affected gland among the three major salivary glands.
Roopashri Rajesh Kashyap   +1 more
doaj  

Generation of functional salivary gland tissue from human submandibular gland stem/progenitor cells

open access: yesStem Cell Research & Therapy, 2020
Background Organ replacement regenerative therapy based on human adult stem cells may be effective for salivary gland hypofunction. However, the generated tissues are immature because the signaling factors that induce the differentiation of human ...
Yi Sui   +8 more
doaj   +1 more source

Clinical Outcomes of Intensity Modulated Proton Therapy for Salivary Gland Carcinoma: High Local Control and Quality of Life Preservation

open access: yesHead &Neck, EarlyView.
ABSTRACT Background In recent years, particle therapy has shown promise as a local treatment for salivary gland carcinoma (SGC); however, its efficacy and safety remain unclear. This study aimed to evaluate the clinical outcomes of intensity‐modulated proton therapy (IMPT) for SGC.
Gaku Takano   +16 more
wiley   +1 more source

AI-based automated Meibomian gland segmentation, classification and reflection correction in infrared Meibography [PDF]

open access: yesarXiv, 2022
Purpose: Develop a deep learning-based automated method to segment meibomian glands (MG) and eyelids, quantitatively analyze the MG area and MG ratio, estimate the meiboscore, and remove specular reflections from infrared images. Methods: A total of 1600 meibography images were captured in a clinical setting.
arxiv  

Efficacy of Eribulin Monotherapy in Patients With Unresectable and/or Metastatic Adenoid Cystic Carcinoma Receiving Platinum‐Based Therapy

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is the second most common and treatment‐resistant salivary gland carcinoma (SGC). Although platinum‐based therapies are effective, the efficacy of eribulin, a microtubule inhibitor with an 18% response rate in a Phase II trial involving recurrent/metastatic SGC, in patients with advanced ACC after ...
Tomomi Sanomachi   +16 more
wiley   +1 more source

Th17 cells play a critical role in the development of experimental Sjogren's syndrome [PDF]

open access: yes, 2015
Objective Although Th17 cells have been increasingly recognised as an important effector in various autoimmune diseases, their function in the pathogenesis of Sjögren's syndrome (SS) remains largely uncharacterised.
Cao, X   +11 more
core   +1 more source

The Translational Role of MUC8 in Salivary Glands: A Potential Biomarker for Salivary Stone Disease?

open access: yesDiagnostics, 2021
Mucin (MUC) 8 has been shown to play an important role in respiratory disease and inflammatory responses. In the present study, we investigated the question of whether MUC8 is also produced and secreted by salivary glands and whether it may also play a ...
Martin Schicht   +8 more
doaj   +1 more source

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