Results 91 to 100 of about 16,765 (226)

Insights into the molecular mechanism of Sjogren's syndrome [PDF]

, 2017
Sjogren’s syndrome (SS) is a chronic autoimmune disease, that affects primarily salivary and lacrimal glands, leading to increased morbidity. Recent studies indicate that loss of salivary gland function is associated with defective cell polarity ...
Langara, Hans A.
core  

IgG4- related disease: an orphan disease with many faces [PDF]

, 2014
Immunoglobulin G4- related disease (IgG4-RD) is a rare systemic fibro-inflammatory disorder (ORPHA284264). Although patients have been described more than 100 years ago, the systemic nature of this disease has been recognized in the 21(st) century only ...
Adelheid Wöhrer, Bastian Oppl, Herwig Pieringer, Ilse Parzer, Jochen Zwerina, Petra Reis   +5 more
core   +3 more sources

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

Sjögren’s syndrome: studying the disease in mice [PDF]

, 2011
Sjögren’s syndrome (SS), a systemic autoimmune disease, is characterized by infl ammation of exocrine tissues accompanied by a signifi cant loss of their secretory function.
Delaleu, Nicolas Hervé, Nguyen, Cuong Q., Peck, Ammon B., Jonsson, Roland   +3 more
core   +2 more sources

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

A morphometric study of human submandibular gland in type 2 diabetic status [PDF]

, 2013
Diabetes Mellitus Type 2 represents one of the principal diseases that afflict the world population. It is well documented that diabetes affects both morphology and function of several organs.
COSSU, MARGHERITA, ISOLA, MICHELA, LILLIU, MARIA ALBERTA, PUXEDDU, ROBERTO, SOLINAS, PAOLA   +4 more
core  

Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease [PDF]

, 2017
IgG4-related disease (IgG4-RD) is characterized by elevated serum IgG4 and marked infiltration of IgG4-positive cells in multiple organs. Interleukin-33 (IL-33) is a recently described cytokine that is secreted by damaged epithelial cells, macrophages ...
Furukawa Sachiko, Hayashida Jun-Nosuke, Iizuka-Koga Mana, Ishiguro Noriko, Maehara Takashi, Miyake Kensuke, Moriyama Masafumi, Nakamura Seiji, Nakashima Hitoshi, Sumida Takayuki, Tanaka Akihiko, Tsuboi Hiroto, Yamauchi Masaki, 住田 孝之, 坪井 洋人   +14 more
core   +1 more source

Ultrasound in Patients With Clinically Suspected Submandibular Gland Disease

Ramathibodi Medical Journal
Background: The submandibular gland is quite common to be affected by various disease processes in all age groups that may be difficult to differentiate clinically. Its superficial location makes it readily accessible to ultrasound evaluation. Objective: To evaluate sonographic features of abnormal submandibular gland.
Phatthawit Tangkittithaworn, Supatcha Khampaen, Suphaneewan Jaovisidha, Rawee Manatrakul, Patarawan Woratanarat, Pawin Numthavaj, Praman Fuangfa   +6 more
openaire   +1 more source

Clinicopathologic Analysis of Sarcomas in the Oral and Maxillofacial Region: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to systematically review primary sarcomas in the oral and maxillofacial region, focusing on patient demographics and sarcoma‐specific characteristics, including clinical presentation, histopathology, treatment approaches, outcomes, and survival rates.
Iara Vieira Ferreira, Reydson Alcides de Lima‐Souza, Talita de Carvalho Kimura, Alfio José Tincani, Marcelo Elias Schempf Cattan, Arthur Antolini‐Tavares, Albina Altemani, Fernanda Viviane Mariano   +7 more
wiley   +1 more source

Artemisinin derivatives modulate KEAP1-NRF2-xCT pathway to alleviate Sjögren’s disease: insights from scRNA-seq and systems biology

Frontiers in Immunology
IntroductionSjögren’s Disease (SJD) is characterized by salivary gland dysfunction, and ferroptosis in salivary gland epithelial cells (SGECs) contributes to glandular damage.
Yong Luo, Liuting Zeng, Yanan Wang, Qianyue Yang, Chang Liu, Xiaojun Tang, Genhong Yao, Lingyun Sun, Lingyun Sun   +8 more
doaj   +1 more source