Results 71 to 80 of about 10,079 (205)

Artemisinin derivatives modulate KEAP1-NRF2-xCT pathway to alleviate Sjögren’s disease: insights from scRNA-seq and systems biology

Frontiers in Immunology
IntroductionSjögren’s Disease (SJD) is characterized by salivary gland dysfunction, and ferroptosis in salivary gland epithelial cells (SGECs) contributes to glandular damage.
Yong Luo, Liuting Zeng, Yanan Wang, Qianyue Yang, Chang Liu, Xiaojun Tang, Genhong Yao, Lingyun Sun, Lingyun Sun   +8 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

The Role of the Mylohyoid Line in the Spread of Mandibular Odontogenic Deep Neck Infection

Oral Diseases, EarlyView.
ABSTRACT Introduction Although mandibular odontogenic deep neck infections are occasionally fatal, the transmission pathway has not been elucidated. Materials and Methods This multicenter retrospective study was comprised of the patients of both sexes who were over 18 years of age and who had mandibular odontogenic deep neck abscesses.
Eiji Iwata, Kyoichi Obata, Shogo Kikuta, Naoki Kaneko, Kotaro Sato, Norio Kitagawa, Yohei Takeshita, Katsuhisa Matsuo, Junsei Sameshima, Akira Tachibana, Shintaro Kawano, Jingo Kusukawa, Masaya Akashi, Soichiro Ibaragi, Joe Iwanaga   +14 more
wiley   +1 more source

Inflammatory Pseudotumor of the Submandibular Gland

Archives of Pathology & Laboratory Medicine, 2001
Abstract We report a rare case of inflammatory pseudotumor arising in the submandibular gland, which presented with autoimmune disease–like clinical manifestations. A 70-year-old Japanese man developed masses in both submandibular regions. Laboratory tests revealed polyclonal hypergammaglobulinemia, high titers of antinuclear antibody,
M, Kojima, S, Nakamura, H, Itoh, T, Suchi, N, Masawa   +4 more
openaire   +2 more sources

Clinicopathological and Prognostic Features of Pleomorphic Adenoma, Recurrent Pleomorphic Adenoma, and Carcinoma ex Pleomorphic Adenoma: A 20‐Year Retrospective Analysis

Oral Diseases, EarlyView.
ABSTRACT Background Pleomorphic adenoma (PA) is the most common salivary gland tumor, and a subset may recur as recurrent PA (RPA) or progress to carcinoma ex pleomorphic adenoma (CXPA). However, comparative evaluations of their biological behavior and prognostic factors remain limited.
Talita de Carvalho Kimura, Luccas Lavareze, Reydson Alcides de Lima‐Souza, Nívia Castro Binda, Carlos Takahiro Chone, Alfio José Tincani, Albina Altemani, Fernanda Viviane Mariano   +7 more
wiley   +1 more source

Longitudinal Changes in Health Utility Scores During the Perioperative Period Among Patients With Oral Cancer: An Analysis of the Effect of Older Age and Social Background

Oral Diseases, EarlyView.
ABSTRACT Objective Many countries have implemented health technology assessment of their public medical insurance programs owing to rising social security costs from ageing populations and expensive emerging medical technologies. Clarifying factors that affect health utility scores is essential for implementing treatments that reflect social values ...
Masashi Sasaki, Takayuki Aoki, Masahiro Uchibori, Masashi Tamura, Yasutaka Hoshimoto, Tsuyoshi Fukuzawa, Banri Tsuda, Yoshihide Ota   +7 more
wiley   +1 more source

Secretory Carcinoma Mimicking a Mucocele: Case Report and Literature Update

Oral Surgery, EarlyView.
ABSTRACT Aim Secretory carcinoma (SC), also known as mammary analogue secretory carcinoma, is a rare malignant neoplasm of the salivary glands, named for its histological and molecular resemblance to mammary secretory carcinoma. The aim of this study is to present a new case of SC occurring in the lower lip, initially diagnosed as a mucocele, and to ...
Débora Frota Colares, André Luis Alves Borges, Leonardo Magalhães Carlan, Adriano Rocha Germano, Antônio de Lisboa Lopes Costa, Hébel Cavalcanti Galvão   +5 more
wiley   +1 more source

Prognostic Factors for Postoperative Complications. An Aggregate Protocol for 10 Observational Studies From the Danish TRIPLE‐A Cohort of 1.2 Million Surgeries

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models.
Anders Peder Højer Karlsen, Asta Prescott, Caroline Folkersen, Jens Laigaard, Atena Saito, Caroline Lando Klammer, Mik Wetterslev, Emil Ipsen Ørskov, Mathilde Fahrendorff, Rebecca Kiær, Helene Holm Laigaard, Nichlas Hovmand, Lars Hyldborg Lundstrøm, Sebastian Buhl Rasmussen, Anders Kehlet Nørskov, Markus Harboe Olsen   +15 more
wiley   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, Volume 78, Issue 7, Page 860-874, July 2026.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, in collaboration with the Consensus Expert Panel (CEP) members, G. Alden Adkins, Brittany Adler, Hossein Ansari, Senada Arabelovic, Alan Baer, Denis Balaban, Shamik Bhattacharyya, Evelyn Bromet, Krishna Chaganti, Kamal Chemali, Melissa Cortez, Schartess Culpepper, Paul Dellaripa, Dana Direnzo, Daniel El Bogdadi, Robert Fearon, Mehrnez Fischbach, Judi Furlong, Christopher Gibbons, Rachael Gordon, Thomas Grader Beck, Syed Haider, Larry Hollenbeck, Chadwick R. Johr, Stuart S. Kassan, Brian King, Octavia Kincaid, Eugene Kissin, Vasileios Kyttaris, Lindsay Lally, Brandon M. Law, Janet Lewis, Scott M. Lieberman, Amanda Lusa, Joseph Lutt, Rashmi Maganti, Arthur M. Mandelin, Sara McCoy, Kerry Neall, Timothy Niewold, Anne Louise Oaklander, Ruben A. Peredo‐Wende, Lynn Petruzzi, Mark A. Porter, Guada Respicio Duque, Tania Reyna, Nathaniel M. Robbins, Elliot D. Rosenstein, Laura Rosow, Breanna Ruthrauff, Amit Sachdev, Nora Sandorfi, Sarah Schafer, Elena Schiopu, Chokkalingam Siva, Daniel Small, Sara M. Stern, Lauren Stiles, Susan Stoddard, Jinny Tavee, Donald Thomas, Edward L. Treadwell, Nagagopal Venna, Steven Vernino, Frederick B. Vivino, Brittany Weber, Sepideh Yadollahi, Huiying Yu, Scott Zashin   +88 more
wiley   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, Volume 78, Issue 7, Page 1393-1402, July 2026.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source