Results 71 to 80 of about 119,912 (302)

Epidermal Interferon‐κ Drives Cutaneous Lupus‐Like Lesions, Photosensitivity, and Systemic Autoimmunity In Vivo

Arthritis &Rheumatology, EarlyView.
Objective Keratinocyte‐derived interferon (IFN) κ is chronically overexpressed in human nonlesional systemic lupus erythematosus (SLE) skin. Recent evidence suggests that epidermal signals instruct the immune system in SLE, but whether epidermal IFNκ alone is sufficient to drive lupus phenotypes has not been investigated.
Benjamin Klein, Deborah J. Colesa, Yiqing Gao, Patrick A. O'Brien, Lin Zhang, Lori Lowe, Kelsey E. McNeely, Nguyen Thi Kim Nguyen, Svenja Henning, Mehrnaz Gharaee‐Kermani, Jeffrey B. Hodgin, Jacob W. S. Martens, Johann E. Gudjonsson, Celine C. Berthier, J. Michelle Kahlenberg   +14 more
wiley   +1 more source

Review of salivary gland neoplasms [PDF]

, 2012
Salivary gland tumours most often present as painless enlarging masses.Most are located in the parotid glands andmost are benign. The principal hurdle in their management lies in the difficulty in distinguishing benign from malignant tumours ...
Chan, JYW, To, VSH, Tsang, RKY, Wei, WI
core   +1 more source

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell‐Targeted Therapies

Arthritis &Rheumatology, Accepted Article.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no FDA‐approved disease‐modifying therapies for SjD.
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Submandibular salivary gland involvement in granulomatosis with polyangiitis

The Egyptian Journal of Bronchology, 2020
Introduction Granulomatosis with polyangiitis (GPA) is one of the forms of small vessel vasculitis. It is a rare condition that needs a high degree of suspicion to reach the diagnosis.
Mohamed F. Abdelghany, Mohammad G. A. Khalaf   +1 more
doaj   +1 more source

Effect of Initial Treatment on Disease Outcome for Patients With Submandibular Gland Carcinoma [PDF]

Archives of Otolaryngology–Head & Neck Surgery, 2007
To elucidate the effect on outcome of initial surgical enucleation with or without definitive surgical resection and radiation therapy for patients with submandibular gland carcinoma.Retrospective clinicopathological review.Tertiary referral center.Eighty-seven consecutive patients (mean follow-up, 8.7 years) with primary submandibular gland carcinoma ...
Scott M, Kaszuba, Mark E, Zafereo, David I, Rosenthal, Adel K, El-Naggar, Randal S, Weber   +4 more
openaire   +2 more sources

A Core Head, Neck, and Neuroanatomy Syllabus for Physical Therapy Student Education

Clinical Anatomy, EarlyView.
ABSTRACT Head, neck, and neuroanatomy are essential components of physical therapy education due to their broad clinical applications. Detailed syllabi exist for medical students, yet none have been developed for physical therapy. This study aimed to produce an International Federation of Associations of Anatomists core head, neck, and neuroanatomy ...
Stephanie J. Woodley, Brooke Willoughby, Alexandra L. Webb, Natasha A. M. S. Flack, Laura Y. Whitburn   +4 more
wiley   +1 more source

A case of IgG4-related hypophysitis maintained remission of diabetes insipidus for over 3 months after completion of steroid treatment

Endocrinology, Diabetes & Metabolism Case Reports, 2023
IgG4-related disease is a multiorgan disorder in which nodules and hypertrophic lesions are observed simultaneously, or separately, in areas including the pancreas, liver, lungs, salivary glands, thyroid glands, and pituitary glands.
Motohiro Kubori, Megumi Fujimoto, Yukiyoshi Okauchi, Kanae Matsuno, Eri Yamabayashi, Ryuki Sakamoto, Shinya Inada, Hiromi Iwahashi   +7 more
doaj   +1 more source

MUC5B levels in submandibular gland saliva of patients treated with radiotherapy for head-and-neck cancer: A pilot study [PDF]

, 2012
Background The salivary mucin MUC5B, present in (sero)mucous secretions including submandibular gland (SMG) saliva, plays an important role in the lubrication of the oral mucosa and is thought to be related to the feeling of dry mouth. We investigated if
AC Houweling, AP Jellema, AV Nieuw Amerongen, C Alliende, Chris H J Terhaard, Cornelis P J Raaijmakers, DG Silva, ECI Veerman, ECI Veerman, EH Pow, Enno C I Veerman, Henk S Brand, JA Langendijk, Judith M Roesink, L Eliasson, LA Tabak, M Little, MK Kam, Petra A M van den Keijbus, PM Braam, R Pramanik, SA Rayment, T Dijkema, Tim Dijkema   +23 more
core   +4 more sources

Mouse parotid salivary gland organoids for the in vitro study of stem cell radiation response

Oral Diseases, 2020
Objective Hyposalivation‐related xerostomia is an irreversible, untreatable, and frequent condition after radiotherapy for head and neck cancer. Stem cell therapy is an attractive option of treatment, but demands knowledge of stem cell functioning ...
Paola Serrano Martinez, D. Cinat, P. Luijk, Mirjam Baanstra, G. Haan, S. Pringle, R. Coppes   +6 more
semanticscholar   +1 more source

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source