A 6-kb promoter fragment mimics in transgenic mice the prostate-specific and androgen-regulated expression of the endogenous prostate-specific antigen gene in humans [PDF]
Prostate-specific antigen (PSA) is a kallikrein-like serine protease, which is almost exclusively synthesized in the luminal epithelial cells of the human prostate. PSA expression is androgen regulated.
Chung, L.W.+6 more
core +3 more sources
Dosimetric and Biologic Differences in Flattened and Flattening-Filter-Free Beam Treatment Plans [PDF]
Purpose: To quantitatively compare the dosimetric and biologic differences in treatment plans from flattened and flattening-filter-free (FFF) beam for three anatomic cancer sites. Methods and Materials: Treatment plans with static intensity-modulated radiotherapy beams and volumetric modulated arc therapy beams were generated for 13 patients for both ...
arxiv
Intermediate Grade Salivary Gland Mucoepidermoid Carcinoma: Is Neck Dissection Indicated?
Abstract Objective NCCN guidelines recommend a neck dissection addressing at least levels II‐IV for high‐grade mucoepidermoid carcinoma (MEC) and close observation of the lymphatic basins for low‐grade MEC. However, no guidelines exist for intermediate‐grade MEC with clinically and radiologically uninvolved cervical lymph nodes.
Jake Langlie+7 more
wiley +1 more source
Role of fine-needle aspiration biopsy in the diagnosis of metastatic desmoplastic melanoma to the parotid and submandibular region [PDF]
SummaryMelanomas are malignant tumors prone to develop in regional and distant metastatic foci. Desmoplastic melanoma is an uncommon melanoma variant that commonly affects the head and neck and can promote early regional metastasis through both lymphatic
Azevedo, A.L.R.+5 more
core +1 more source
Abstract An 11‐year‐old, female West Highland white terrier presenting cough, emesis, diarrhoea and hyporexia refractory to symptomatic treatment was subjected to endoscopy showing increased palatine tonsil region. Biopsy findings revealed a carcinoma. Computed tomography also showed an increased right medial retropharyngeal lymph node dorsally related
Jiuli R. S. de Salles+2 more
wiley +1 more source
Lymphadenopathy may be caused due to various reasons, most common being infections, neoplasms and immunologic disorders. Considering the frequent use of biomaterials in dentistry, it is not uncommon to find allergic reactions in the oral mucosa.
Rohan Pulgaonkar, P. Chitra, Zama Moosvi
semanticscholar +1 more source
Submandibular gland carcinoma ex pleomorphic adenoma clinically mimicking a benign lesion
Carcinoma expleomorphic adenoma (CXPA) is a malignant carcinoma arising from a primary or recurrent benign pleomorphic adenoma. The lesion is recognized to be an aggressive malignancy with high recurrence rates and a high metastatic rate.
Grace Paka Lubamba+6 more
doaj
A case of secretory carcinoma of the submandibular gland with unusual immunohistochemical staining
Mammaglobin negative secretory carcinoma may be overlooked. It is important to assess the possibility of diagnosis when histology is suggestive and immunohistochemical staining for S‐100 is positive even when staining for mammaglobin is negative.
Alexander Karabachev+3 more
doaj +1 more source
Immunohistochemical expression of p21 in normal tissues of salivary gland, pleomorphic adenoma and carcinoma ex pleomorphic adenoma (undifferentiated and adenocarcinoma types) [PDF]
Objective: Our study aimed to characterize alteration in the immunohistochemical expression of p21 in normal tissue of the salivary gland surrounding pleomorphic adenoma, the tumor cells of pleomorphic adenomas, and carcinoma arising in pleomorphic ...
Nassani, Mohammad Z., Tarakji, Bassel
core +1 more source
Cytological Pattern of Salivary Gland Lesions
To study the cytological pattern of salivary glands swellings on fine needle aspiration cytology (FNAC). Methods: Patients who underwent fine needle aspiration cytology (FNAC) for their salivary gland swellings, were included.
Abdul Rauf
doaj