Results 41 to 50 of about 12,854 (263)

A “Yellow Submarine” in Dermoscopy

Open Access Macedonian Journal of Medical Sciences, 2018
BACKGROUND: Histiocytic sarcoma (HS) is an extremely rare, non-Langerhans cell tumor. HS affects especially adults, its etiology is unknown yet. Skin could be interested by papules or nodules, single or multiple.  CASE REPORT: A Caucasian man in his late 40s came to our clinic for a naevi evaluation.
Satolli, Francesca, Rovesti, Miriam, Zucchi, Alfredo, GANDOLFI, MARCO, Feliciani, Claudio, Tchernev, Georgi, Wollina, Uwe, Gianfaldoni, Serena, Lotti, Torello   +8 more
openaire   +4 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Doppler Compensation Techniques for M-Ary Sequence Spread Spectrum Signals Based on Correlation Cost Factors in Mobile Underwater Acoustic Communication

Journal of Marine Science and Engineering
Unlike terrestrial radio, the speed of sound in the ocean is relatively slow, which results in mobile underwater M-ary spread spectrum communication typically exhibiting significant and variable multipath effects along with strong Doppler effects ...
Yubo Han, Shuping Han, Heng Zhao, Yaohui Hu, Jingfeng Xu, Gang Yang   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Multi-USV Task Assignment Based on NSGA II-MC

IEEE Access
With the development of artificial intelligence technology, the level of autonomy of unmanned platforms is continuously improving. They are capable of completing certain specific tasks based on external information inputs and can achieve battlefield ...
Yonghao Zhang, Xueman Fan, Zhuo Cheng, Changyou Xue   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Attention-Augmented LSTM Feed-Forward Compensation for Lever-Arm-Induced Velocity Errors in Transfer Alignment

Biomimetics
In a mother–child underwater bio-inspired robotic system, the equivalent lever arm between the master and slave inertial navigation systems (INSs) varies with launcher attitude changes and structural flexure.
Shuang Pan, Guangyao Yan, Dongping Sun, Binghong Liang, Linping Feng   +4 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source