Results 181 to 190 of about 222,123 (244)

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray   +16 more
wiley   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild   +3 more
wiley   +1 more source

<i>Operando</i> NMR Monitoring of Electrochemical Reactions. [PDF]

open access: yesOrg Process Res Dev
Lee KS   +4 more
europepmc   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

β‐hydroxy‐β‐methylbutyrate improves fast‐twitch muscle function, histopathology and mitochondrial respiration in the D2.mdx dystrophic mouse

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend β‐Hydroxy‐β‐methylbutyrate (HMB) enhances fast‐twitch muscle and mitochondrial function in D2.mdx mice. Male DBA/2J (wild‐type) and D2.mdx mice aged 3 or 6 months received daily β‐hydroxy‐β‐methylbutyrate (HMB; 1 mg g−1 day−1) via drinking water for 8 weeks. Fast‐twitch extensor digitorum longus (EDL) and slow‐twitch soleus (SOL)
Nicholas Giourmas   +5 more
wiley   +1 more source

Instrumentation and control in a laboratory-scale process for CO<sub>2</sub> capture post-combustion. [PDF]

open access: yesHardwareX
Silva León MF   +4 more
europepmc   +1 more source

Comparison of the Clinical Outcomes Between Gel Immersion and Underwater Endoscopic Mucosal Resection for Superficial Non‐ampullary Duodenal Epithelial Tumors (With Video)

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objective Gel immersion endoscopic mucosal resection (GIEMR) has recently emerged as a novel technique for superficial non‐ampullary duodenal epithelial tumors (SNADETs). However, its clinical advantages over underwater EMR (UEMR) remain unclear. This study compared the short‐ and long‐term outcomes of GIEMR and UEMR for SNADETs.
Mitsuru Otsuka   +16 more
wiley   +1 more source

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