Advanced Science, EarlyView.Tian et al. reveal that FH K112 lactylation is elevated after TBI, leading to fumarate accumulation, mitochondrial damage, mtDNA release and amplified neuroinflammation. AARS2 and SIRT3 act as the “writer” and “eraser” for FH K112 lactylation. The peptide Pep‐K112 targeting this site alleviates brain injury, highlighting a potential therapeutic target.
Yang Tian +21 more
wiley +1 more source
A low-cost continuous rumen simulation system for sustainable in vitro fermentation and feed evaluation in ruminant production. [PDF]
MethodsXKour H, Malik R, Datt C, Rana P.
europepmc +1 more source
Advanced Science, EarlyView.Contextual cues recruit the glutamatergic vCA1–dmPFC pathway to retrieve morphine reward memory by reshaping cell‐type‐specific prefrontal microcircuit activity. Distinct regulation of PV+ and SST+ interneurons defines this hippocampal–prefrontal mechanism.
Zhifeng Shi +8 more
wiley +1 more source
Effects of Aquatic Exercise on Balance, Motor Function and Neuromuscular Performance in Children and Young Adults with Disabilities: A Systematic Review. [PDF]
Healthcare (Basel)Cánovas FJ +4 more
europepmc +1 more source
Advanced Science, EarlyView.High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling +18 more
wiley +1 more source
IoT-Based Precision Irrigation System Featuring Multi-Sensor Monitoring and Scheduled Automated Water-Control Gates for Rice Production. [PDF]
Sensors (Basel)Mahmud MNH, Dong Y, Alam MM, Sharmin J.
europepmc +1 more source
Effect of Submersible Motor Temperature on Diagnostic Insulation Parameters
, 2020 V. Trushkin +2 more
semanticscholar +1 more source
Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading
Advanced Science, EarlyView.Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong +5 more
wiley +1 more source
PSO-optimized electronic load controller with intelligent energy recovery for self-excited induction generator based micro-hydro systems. [PDF]
Sci RepSinha S, Rajak MK, Pudur R.
europepmc +1 more source
Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications
Advanced Science, EarlyView.Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen +11 more
wiley +1 more source