Results 211 to 220 of about 2,539,037 (338)

Deep eutectic solvents as recyclable media for metal removal from crude oil. [PDF]

RSC Adv
Mirinn E, Abbott AP, Kilpatrick AFR.
europepmc   +1 more source

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

Advanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu, Zitian Zheng, Feiran Wang, Huanhuan Luo, Fei Ju, Yucheng Zhu, Zheng Zhou, Jie Sun, Zhenghui Qiu, Xiang Luo, Zhongzheng Jia, Jianquan Wang, Hongjie Huang, Bo Zhang   +13 more
wiley   +1 more source

Operando detection of dissolved oxygen in fluid solution using a submersible rapid scan EPR on a chip dipstick sensor. [PDF]

Sci Rep
McPeak JE, Segantini M, Marcozzi G, Dona I, Künstner S, Chu A, Kern M, Poncelet M, Driesschaert B, Anders J, Lips K.   +10 more
europepmc   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

Advanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan, Yan Zheng, Yue Lan, Zhuo Cheng, Siya Wang, Changqing Li, Yanqiu Wang, Minghan Liu   +7 more
wiley   +1 more source

An uncertainty approach for Electric Submersible Pump modeling through Deep Neural Network. [PDF]

Heliyon
Almeida Costa E, de Menezes Rebello C, Viena Santana V, Reges G, de Oliveira Silva T, Santana Luiz de Abreu O, Pellegrini Ribeiro M, Pereira Foresti B, Fontana M, Bessa Dos Reis Nogueira I, Schnitman L.   +10 more
europepmc   +1 more source

A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior

Advanced Science, EarlyView.
Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li, Ying‐Dan Zhang, Wei Wang, Xin‐Yi Wu, Di Li, Xin Gong, Fei Tian, Meng‐Yu Dai, Jian Gao, Zi‐Feng Zheng, Zi‐Yang Bi, Dong‐Dong Shi, Zhen Wang   +12 more
wiley   +1 more source

Smartphone‐Guided Visible Light Modulation of RSNOs for Antimicrobial Activity via Controlled Nitric Oxide Release

Advanced Science, EarlyView.
A light‐activated catheter insert combines antimicrobial blue light with nitric oxide release to generate complementary oxidative and nitrosative stress, producing potent broad‐spectrum antimicrobial activity. The approach achieves greater than 4‐log reductions in bacterial and fungal viability and significantly reduces Staphylococcus aureus ...
Alexander Bruckmann, Adam Brooks Goodman, Myddelton C. Parker, Mark Garren, Ji Eun Park, Chad Schmiedt, Hitesh Handa, Elizabeth J. Brisbois   +7 more
wiley   +1 more source

Hybrid physics-informed artificial intelligence for high-fidelity modeling and optimization of electrical systems. [PDF]

Front Artif Intell
Nyangon J.
europepmc   +1 more source

Active Oscillations of Elastic Membranes Arising from the Coupling with a Catalytic Reaction

Advanced Science, EarlyView.
Coupling an elastic membrane to a catalytic reaction produces active oscillations that self‐sustain for hours: the membrane cyclically inflates and deflates as the reaction spontaneously activates and deactivates, without external power. Energy release is directly embodied in the oscillation dynamics, opening elasto‐chemical strategies for the physical
Alberto Comoretto, Samuel D. Gollob, Erik Steur, Kaitlyn P. Becker, Ellen T. Roche, Johannes T.B. Overvelde   +5 more
wiley   +1 more source

An experimental evaluation of vibration patterns arising from vortex flow in mixed flow pumps a case study in Upper Egypt. [PDF]

Sci Rep
El-Gazzar DMS, Abo-Elnil AHI, Elsayed MEA.   +2 more
europepmc   +1 more source