Results 181 to 190 of about 1,886 (262)

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

In Situ Analytical Chemistry Laboratory for the Exobiology Extant Life Surveyor. [PDF]

ACS Meas Sci Au
Drevinskas T, Cable ML, Stenner C, Gardner AS, Paton M, Malaska MJ, Cruz S, Rieber R, Etheredge R, Robinson M, Ono M, Mora MF, Bagshaw EA, Prior-Jones MR, Ferreira Santos MS, Noell AC, Willis PA.   +16 more
europepmc   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, EarlyView.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Research on Multiphyics bidirectional coupling for small-diameter high-speed submersible permanent magnet synchronous motor. [PDF]

Heliyon
Tan L, Wang Y, Wu Y, Wang T, Cui J, Wang H.   +5 more
europepmc   +1 more source

Effect of Medication Intake on Dental Implant‐Related Outcomes—A Scoping Review

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objective The objective of this scoping review was to evaluate the effect of systemic medications on dental implant outcomes in medically compromised patients. Material and Methods Electronic and manual searches were conducted for this scoping review.
Alberto Monje, Maria Costanza Soldini, Emilio Couso‐Queiruga, Álvaro Babiano, Vivianne Chappuis   +4 more
wiley   +1 more source

Evaluation and selection of the best artificial lift method for optimal production using PIPESIM software. [PDF]

Heliyon
Janadeleh M, Ghamarpoor R, Kadhim Abbood N, Hosseini S, Al-Saedi HN, Hezave AZ.   +5 more
europepmc   +1 more source

Optimized control, and experimental validation of a novel multi-stage parabolic trough collector for solar water heating systems. [PDF]

Sci Rep
AbdelFatah RT, Shalaby R, Fahim IS, Kasem MM.   +3 more
europepmc   +1 more source

The Moral Consequences of the Arendtian Space of Freedom

Constellations, EarlyView.
Seung‐Hwan Hong
wiley   +1 more source

The aesthetic sublime of megaproject structures: A framework and a research agenda

European Management Review, EarlyView.
Abstract The physical structures of megaprojects—such as mega‐canals, metros, railway lines, bridges, tunnels, and iconic opera houses—hold a profound capacity to generate aesthetic experiences with enduring societal impact. Yet, research on megaprojects has predominantly focused on functionality and economic rationale with aesthetics being pushed to ...
Federica De Molli, Alfons van Marrewijk, Arne Carlsen   +2 more
wiley   +1 more source

PSO-optimized electronic load controller with intelligent energy recovery for self-excited induction generator based micro-hydro systems. [PDF]

Sci Rep
Sinha S, Rajak MK, Pudur R.
europepmc   +1 more source