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Tick subolesin is an ortholog of the akirins described in insects and vertebrates [PDF]
Developmental and Comparative Immunology, 2009 The tick protective antigen, subolesin, is a regulatory protein involved in the control of multiple cellular pathways. Subolesin is evolutionary conserved in invertebrates and vertebrates with sequence homology to akirins, a recently renamed group of ...
José de la Fuente +2 more
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Vaccine, 2009 Dermanyssus gallinae has a worldwide distribution and is considered to be the most serious and economically significant ectoparasite affecting egg-laying poultry in Europe.
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Vaccine, 2011 Tick subolesin was shown in immunization trials using the recombinant protein to protect hosts against tick infestations. In this study, we demonstrated that subolesin vaccination and release of ticks after subolesin knockdown by RNA interference (RNAi) could be used for the control of Rhipicephalus (Boophilus) microplus tick infestations in cattle and
José de la Fuente +2 more
exaly +7 more sources
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Mapping protective epitopes in the tick and mosquito subolesin ortholog proteins
Vaccine, 2010The tick protective antigen, subolesin, is a structural and functional ortholog of insect akirins, an evolutionary conserved group of proteins that regulate gene expression thus affecting multiple cellular processes such as digestion, immune response, reproduction and development.
José de la Fuente +2 more
exaly +4 more sources
Defining the Role of Subolesin in Tick Cell Culture by Use of RNA Interference
Annals of the New York Academy of Sciences, 2008Development of tick vaccines provides new opportunities for control of tick infestations and tick‐borne diseases. Recently, the tick‐protective protein, subolesin, was identified in a cell line derived from Ixodes scapularis by expression library immunization and a mouse model of tick infestations.
José de la Fuente +1 more
exaly +3 more sources
Vaccine, 2020 Vaccination against ticks is an environmentally friendly alternative control method compared to chemical acaricide applications. Subolesin is a conserved protein in ticks, which can provide protection against some tick species. In this study, we evaluated the capacity of cocktail vaccination with Subolesin and ribosomal acidic protein 0 (P0) peptide ...
Ibrahim Hassan +2 more
exaly +3 more sources
Veterinary Parasitology, 2012 29 p., 3 tablas, 4 figurasSubolesin/akirin is a well characterized protective antigen highly conserved across vector species and thus potentially useful for the development of a broad-spectrum vaccine for the control of arthropod infestations including ...
Ricardo Perez Sanchez +2 more
exaly +2 more sources
Veterinary Parasitology, 2021
The cattle tick Rhipicephalus microplus affect animal health, welfare, and cattle production in tropical and subtropical zones of the world. Anti-tick vaccines have been an effective alternative for cattle tick control instead of traditional chemical products.
Rodolfo Esteban Lagunes Quintanilla +2 more
exaly +3 more sources
The cattle tick Rhipicephalus microplus affect animal health, welfare, and cattle production in tropical and subtropical zones of the world. Anti-tick vaccines have been an effective alternative for cattle tick control instead of traditional chemical products.
Rodolfo Esteban Lagunes Quintanilla +2 more
exaly +3 more sources
Experimental and Applied Acarology, 2015
Subolesin is a well-characterized protective antigen in many ticks and, thus, it is potentially useful in the development of a broad-spectrum vaccine or an autocidal gene silencing strategy to control tick infestations. A subolesin homolog was cloned from the tick Rhipicephalus haemaphysaloides, which is widespread in China, by rapid amplification of ...
Pengyun, Lu +7 more
openaire +2 more sources
Subolesin is a well-characterized protective antigen in many ticks and, thus, it is potentially useful in the development of a broad-spectrum vaccine or an autocidal gene silencing strategy to control tick infestations. A subolesin homolog was cloned from the tick Rhipicephalus haemaphysaloides, which is widespread in China, by rapid amplification of ...
Pengyun, Lu +7 more
openaire +2 more sources
Vaccine, 2014
Identification of cross-protective tick vaccine antigens is a challenging area of veterinary research. To address this challenge, a recently identified candidate tick protective antigen, Subolesin (SUB), was targeted in this research. The conservation of subolesin ortholog of Hyalomma anatolicum and Rhipicephalus (Boophilus) microplus across different ...
José de la Fuente +2 more
exaly +3 more sources
Identification of cross-protective tick vaccine antigens is a challenging area of veterinary research. To address this challenge, a recently identified candidate tick protective antigen, Subolesin (SUB), was targeted in this research. The conservation of subolesin ortholog of Hyalomma anatolicum and Rhipicephalus (Boophilus) microplus across different ...
José de la Fuente +2 more
exaly +3 more sources