Results 181 to 190 of about 50,095 (352)

Is a Clinical Trial With a Non‐Bioequivalent Batch Necessary? The Critical Role of Intrasubject Variability in Olaparib Formulation Bridging by PBPK

Clinical Pharmacology &Therapeutics, EarlyView.
Although physiologically based pharmacokinetic (PBPK) modeling is increasingly being used to support oral drug formulation bridging, the acceptance by regulatory agencies is low. One of the primary concerns is the absence of clinical pharmacokinetic (PK) data from a non‐bioequivalent (non‐BE) batch during model validation.
Jin Dong, Andrea Moir, Xavier Pepin, Elizabeth Lowe, Sandy Hopkins, Weifeng Tang, Diansong Zhou   +6 more
wiley   +1 more source

Responder perspectives on preparedness for healthcare needs of vulnerable populations during floods and heatwaves: a qualitative study in Emilia-Romagna, Italy. [PDF]

BMJ Public Health
Soldà G, Molsted-Alvesson H, Montalti M, Reali C, Gori D, Von Schreeb J, Ljungman P.   +6 more
europepmc   +1 more source

Physician Ownership for the Virtuous Practice of Medicine. [PDF]

Linacre Q, 2023
Joa B.
europepmc   +1 more source

“Train and Hope”: The Role of Restorative Justice Coordinators in Sustaining a Culture of Care in Schools

Conflict Resolution Quarterly, EarlyView.
ABSTRACT This article examines the role of restorative justice coordinators in supporting teachers and schools in adopting a whole‐school approach to restorative justice in education. Coordinators are often tasked with implementing a train‐and‐hope model, in which they receive initial training in restorative justice but are largely left unsupported ...
Crystena Parker‐Shandal, Kristina R. Llewellyn, Sandeep Manku, Mackenzie Leclaire   +3 more
wiley   +1 more source

Regional health security architecture in ASEAN countries: Lessons from regional CDC models and Japan's strategic partnership for ACPHEED development. [PDF]

Glob Health Med
Miyano S, Nozaki I, Hachiya M, Miyamoto T, Takei T.   +4 more
europepmc   +1 more source

The Relationship between the European Commission and Courts of the Member States in the Enforcement of EU Competition Law in Light of Decentralisation and Subsidiarity as Part of New Governance

, 2012
Madleen Düdder
openalex   +1 more source

Sustainable Development, Environmental Certification and the Financial Performance of the Road Passenger Transportation Sector

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Within the framework of sustainable development and environmental policy, environmental certification is regarded as a mechanism through which road passenger transport companies (RPTCs) could mitigate their adverse environmental impacts and attain competitive advantages that may enhance their financial performance.
Jose Antonio Cavero‐Rubio, Monica Gonzalez‐Morales   +1 more
wiley   +1 more source

Decolonising global health: why the new Pandemic Agreement should have included the principle of subsidiarity. [PDF]

Lancet Glob Health
de Campos-Rudinsky TC, Bosha SL, Wainstock D, Sekalala S, Venkatapuram S, Atuire CA.   +5 more
europepmc   +1 more source

Subsidiarity and multi-level governance [PDF]

, 2012
De Ville, Ferdi, Loisen, Jan
core  

Using Financial and Sustainability Ratios to Map Sectors. An Approach With Compositional Data

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The article aims to visualize in a single graph Spanish fish and meat processing companies with respect to solvency, energy, waste and water intensity and gender employment gap. These financial, environmental, and social indicators are ratios, which require specific statistical analysis methods.
Elena Rondós‐Casas, Núria Arimany‐Serrat, Miquel Carreras‐Simó, Germà Coenders   +3 more
wiley   +1 more source