Results 131 to 140 of about 1,322,584 (361)

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

A narrative review of trends and challenges of substance use in Punjab: a 10-year analysis of data from 2015 to 2024

Discover Public Health
Background Punjab, a northwestern state of India, is experiencing a serious substance use crisis with wide-ranging public health, social, and economic consequences.
Heena Sachdeva, Manish Sharma, Maninder
doaj   +1 more source

Families that Live with Disorders Related to Substances and Addiction [PDF]

, 2017
Cassandra Borges Borton
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Profiles of quality of outpatient care use, associated sociodemographic and clinical characteristics, and adverse outcomes among patients with substance-related disorders. [PDF]

Subst Abuse Treat Prev Policy, 2023
Fleury MJ, Cao Z, Grenier G, Huỳnh C.
europepmc   +1 more source

Pertanggungjawaban Kriminal Orang Dengan Gangguan Jiwa [PDF]

, 2015
Criminal responsibility is an important factor in criminal offense. Determining a criminal responsibility of people with mental disorders is problematic.
, Dr. Natangsa Surbakti, S.H., M.Hum, , Wardah Yuspin, S.H.,M.Kn.,Ph.D., Herdaetha, Adriesti   +2 more
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Heroin Overdose-Related Child and Adolescent Hospitalizations: Insight on Comorbid Psychiatric and Substance Use Disorders [PDF]

, 2019
Uwandu Queeneth, Narmada Neerja Bhimanadham, Pranita Mainali, Henry Onyeaka, Amaya Pankaj, Rikinkumar S. Patel   +5 more
openalex   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Predictors of Death From Physical Illness or Accidental/Intentional Causes Among Patients With Substance-Related Disorders. [PDF]

Can J Psychiatry, 2023
Fleury MJ, Cao Z, Grenier G, Huỳnh C.
europepmc   +1 more source