Results 161 to 170 of about 1,322,584 (361)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Difficulties with interferon treatment in former intravenous drug users

Brazilian Journal of Infectious Diseases
OBJECTIVES: Intravenous drug use accounts for most of the new hepatitis C infections worldwide. Although there is an urgent need for antiviral treatment of infected intravenous drug users (IDUs), several factors compromise their treatment including lack ...
Gábor Gazdag, Gergely Horváth, Olga Szabó, Gabor S Ungvari   +3 more
doaj   +1 more source

The Economic Burden of Pharmaceuticals in People Diagnosed with Depression, Anxiety-Related Disorder and Substance use in Australia [PDF]

, 2015
Yuan Xin Lee, Anne Magnus, ML Chatterton, Cathrine Mihalopoulos   +3 more
openalex   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Regional Variation in Attitude of Mental Health Professionals Towards Tackling Illicit Drug-use and Drug-related Disorders [PDF]

, 2017
This study sought to assess the attitudes of Mental Health Professionals (MHPs) towards tackling illicit drug use and drug-related disorders in Nigeria and to explore regional variations in attitude. Based on the validated Substance Abuse Attitude Survey
Akinola, O. (Olubusayo), Kuo, W. (Wen-Hung), Obisesan, O. (Olawunmi), Oswald, J. (John)   +3 more
core  

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Attenuation of Withdrawal Signs, Blood Cortisol, and Glucose Level with Various Dosage Regimens of Morphine after Precipitated Withdrawal Syndrome in Mice

Iranian Journal of Medical Sciences, 2016
Morphine withdrawal usually results in unsuccessful outcomes. Despite partial benefits from alternative substances such as methadone, its use may not lead to the desired result due to the lack of mental tranquility during the withdrawal period.
Majid Motaghinejad, Goudarz Sadeghi-Hashjin, Mohammad Kazem Koohi, Seyed Morteza Karimian   +3 more
doaj  

Substance-Related Disorder [PDF]

, 2020
openaire   +1 more source

Gender-related patterns and determinants of recent help-seeking for past-year affective, anxiety and substance use disorders: findings from a national epidemiological survey [PDF]

, 2015
Meredith Harris, Amanda Baxter, Nicola Reavley, Sandra Diminic, Jane Pirkis, Harvey Whiteford   +5 more
openalex   +1 more source