Results 191 to 200 of about 1,329,001 (340)

The influence of tightening regulations on patients with new psychoactive substance-related disorders in Japan. [PDF]

Neuropsychopharmacol Rep, 2018
Tanibuchi Y, Matsumoto T, Funada D, Shimane T.   +3 more
europepmc   +1 more source

Family Functioning and Quality of Life among Families in Eating Disorders: A Comparison with Substance-related Disorders and Healthy Controls.

European eating disorders review, 2016
Dimitra Anastasiadou, A. R. Sepúlveda, Julio C. Sánchez, M. Parks, T. Álvarez, M. Graell   +5 more
semanticscholar   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Substance Use: Family-based Interventions to Prevent Substance Use Among Youth

The Community Preventive Services Task Force (CPSTF) findings and recommendations for "Substance Use: Family-based Interventions to Prevent Substance Use Among Youth" are based on systematic reviews of evidence of effectiveness and economic impact.

core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Substance use disorders in military veterans: prevalence and treatment challenges

, 2017
Jenni B Teeters,1,2 Cynthia L Lancaster,1,2 Delisa G Brown,3 Sudie E Back1,2 1Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, USA; 2Ralph H Johnson Veterans Affairs (VA) Medical Center, Charleston ...
Brown DG, Teeters JB, Lancaster CL, Back SE   +3 more
core  

Physicians' attitudes towards patients with substance-related disorders predict training needs in addiction medicine: challenges and opportunities for strengthening the global addiction medicine workforce. [PDF]

BMC Med Educ
Pinxten WJL, Fitriana E, Jokūbonis D, Adomaitiene V, Leskauskas D, Hutschemaekers GJM, De Jong CAJ.   +6 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Co-occurring trauma- and stressor-related and substance-related disorders in youth: A narrative review. [PDF]

Med Res Arch
Hinckley JD, Adams ZW, Dellucci TV, Berkowitz S.   +3 more
europepmc   +1 more source