Results 251 to 260 of about 2,947,412 (335)

Psychiatric Comorbidities and Sociodemographics of Patients Diagnosed with Pyromania Admitted to a Community Psychiatric Hospital in Bronx, New York: Retrospective Chart. [PDF]

Indian J Psychol Med
Joshaghani N, Sharma V, Taneja G, Jiménez-Parrado LD, Hartnett R, Mitra S, Gunturu S.   +6 more
europepmc   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Lifetime Adversity Among Individuals With Early Phase Psychosis and Comorbid Substance Misuse. [PDF]

Early Interv Psychiatry
Patterson VC, Gillis BAJ, Sawers J, Pencer A, Simmons M, Church R, Adams GC, Carley S, Adams S, Tibbo PG.   +9 more
europepmc   +1 more source

Humic substance and phosphorus sources in red latosol and quartzipsamment

, 2015
Lucas Morais Lôbo
openalex   +1 more source

A novel application in the study of client language: Alcohol and marijuana-related statements in substance-using adolescents during a simulation task.

, 2016
Benjamin O. Ladd, Tracey A. Garcia, Kristen G. Anderson   +2 more
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Substance Use, Poor Sleep, and Gestational Diabetes: Concerns in Adolescent Pregnancy. [PDF]

Sleep Sci
Dokkedal-Silva V, Hirata AE, Berro LF, Galduróz JCF, Tufik S, Andersen ML.   +5 more
europepmc   +1 more source

Pick A Substance. Any Substance. [PDF]

Chemical & Engineering News Archive, 1997
openaire   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source