Results 61 to 70 of about 811,040 (248)

Exploring the Potential Impact of GLP-1 Receptor Agonists on Substance Use, Compulsive Behavior, and Libido: Insights from Social Media Using a Mixed-Methods Approach

open access: yesBrain Sciences
Glucagon-like peptide-1 (GLP-1) is involved in a range of central and peripheral pathways related to appetitive behavior. Hence, this study explored the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on substance and behavioral ...
Davide Arillotta   +6 more
doaj   +1 more source

Factors associated with drug checking service utilization among people who use drugs in a Canadian setting

open access: yesHarm Reduction Journal, 2020
Background The United States and Canada are amidst an opioid overdose crisis, with the Canadian province of British Columbia (BC) among the hardest hit. In response, drug checking services (DCS) have been introduced in this setting as a novel pilot harm ...
Viseth Long   +9 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

FARABİ'NİN DÜALİZMİ

open access: yesFelsefe Dünyası, 2008
Eyüp ŞAHİN, "FARABİ'NİN DÜALİZMİ", FELSEFE DÜNYASI DERGİSİ, SAYI ...
Eyüp Şahin
doaj  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Factorial structure and reliability and validity of Turkish Version the Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES) in male alcohol dependent inpatients

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objective: The Stages of Change Readiness and Treatment Eagerness Scale (SOCRATES), is a 19-item self-rating scale developed by Miller and Tonigan (1996) for screening motivation and readiness to change dirinking - related behavior.
Cüneyt Evren   +2 more
doaj  

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Smoking, alcohol, and substance use and rates of quitting during pregnancy: is it hard to quit?

open access: yesInternational Journal of Women's Health, 2016
Ahmet Bulent Yazici,1 Hilal Uslu Yuvaci,2 Esra Yazici,3 Ebru Halimoglu Caliskan,4 Arif Serhan Cevrioglu,2 Atila Erol3 1Department of Psychiatry, Training and Research Hospital, 2Faculty of Medicine, Department of Obstetrics and Gynaecology, 3Faculty of ...
Yazici AB   +5 more
doaj  

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