Results 191 to 200 of about 841,730 (362)

PIEZO Force Sensing in Vascular Biology: An Explosion of New Knowledge, Concepts and Opportunity

open access: yesAdvanced Science, EarlyView.
Knowledge of the remarkable mechanical force sensing and electrically transducing PIEZO1 and PIEZO2 channels is discussed across vascular biology and its cell types from the embryonic to adult stages in health, disease and old age. How the channels work, relate to other factors and signal for tissue responses to mechanical forces is debated.
David J Beech
wiley   +1 more source

Novel Role of Gut‐Derived Roseburia Intestinalis in Safeguarding Intestinal Barrier Integrity and Microenvironment Homeostasis During Arsenic Exposure

open access: yesAdvanced Science, EarlyView.
Arsenic exposure disrupts intestinal barriers and gut microenvironment. Fecal microbiota transplantation (FMT) alleviates arsenic‐induced damage, with gut‐derived Roseburia intestinalis (R.i) identified as a key protective strain. R.i administration counters arsenic toxicity through immunomodulatory pathways and metabolites.
Lixiao Zhou   +15 more
wiley   +1 more source

Retinitis Pigmentosa‐Associated Gene TRIM49 Regulates ULK1‐Mediated Autophagy and Photoreceptor Phagocytosis by the Retinal Pigment Epithelium

open access: yesAdvanced Science, EarlyView.
Based on next‐generation sequencing data of retinitis pigmentosa (RP) patients and controls, this study identifies TRIM49 as a novel gene for autosomal recessive RP. TRIM49 is specifically expressed in the retinal pigment epithelium (RPE) of human retina.
Zhen Yi   +17 more
wiley   +1 more source

Interface‐Adaptive Dual‐Color Hydrogel with Self‐Repairing Function and High Adhesion as Flexible Wearable Sensor for Minimally‐Invasive Monitoring Pesticide Residue in Living Crop

open access: yesAdvanced Science, EarlyView.
Dual‐color hydrogel TPE@Mn@ZnS@AG@PVA is prepared using b‐TPE NPs and r‐Mn@ZnS QDs as blue‐channel and red‐channel indicators, exhibits smart interface adaptability, high adhesion, good self‐repairing function, and superior response to thiophannate‐methyl, and thus acts as a flexible wearable sensor for in situ, on‐site and minimally‐destructive ...
Jianling Chen   +8 more
wiley   +1 more source

Prevalence and Correlates of Substance Abuse Among Healthcare Students. [PDF]

open access: yesScientificWorldJournal
Magableh RM   +3 more
europepmc   +1 more source

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