Results 191 to 200 of about 981,064 (308)

Harm Reduction [PDF]

, 2005
Fischer, B
core   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Unshackling our youth from the chains of substance abuse as disaster risk. [PDF]

Front Public Health
Sobane K, Lunga W, Ramaphakela T, Baloyi C.   +3 more
europepmc   +1 more source

Helicobacter pylori‐Induced Persistent IGF2BP1 Activation Promotes Ferroptosis Resistance in Gastric Tumorigenesis

Advanced Science, EarlyView.
Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning, Xin Guan, Xinyu Hao, Jing Zhang, Deyao Li, Ying Xiong, Wenlin Zhang, Xiurui Han, Yanfei Lang, Meiling Zhou, Mengjie Yang, Zhi Huang, Tinghui Qu, Ming Zu, Qiao Meng, Weiwei Fu, Fengmin Lu, Jing Zhang, Xiangmei Chen, Tong Liu, Shigang Ding   +20 more
wiley   +1 more source

OSAM semi-annual reports

Semiannual; Electronic coverage as of Sept. 26, 2006: June 1999/Jan. 2000-; Description based on: June 1999/Jan. 2000 issue; title from cover of PDF (viewed Sept.
Ohio Substance Abuse Monitoring Network.
core  

A cooperative agreement for workforce development in vietnam: HIV-addiction technology transfer center (VH-ATTC)

Annals of Global Health, 2015
K. Darfler, S. Larkins, R. Rawson, G. Le Minh   +3 more
doaj   +1 more source

Bidirectional Associations Between Substance Abuse and Psoriasis: A Prospective Cohort Study. [PDF]

Psoriasis (Auckl)
Che X, Zhou J, Wang A, Guo J, Zhang C, Xiao Y.   +5 more
europepmc   +1 more source

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

Advanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen, Huan Chen, Sining Ding, Fan Liu, Xiaofei Zheng, Yuan Wang, Ruitu Tian, Huan Li, Peilin Liu, Le Hu, Bin Liu, Limin Rong, Mangmang Li   +12 more
wiley   +1 more source

Substance abuse in first-episode psychosis at Chris Hani Baragwanath Hospital. [PDF]

S Afr J Psychiatr
Shandu PN, Minty Y.
europepmc   +1 more source