Results 121 to 130 of about 878,624 (401)

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

open access: yesAdvanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao   +12 more
wiley   +1 more source

The role of attributions in abstinence, lapse, and relapse following substance abuse treatment [PDF]

open access: green, 1994
Maureen A. Walton   +2 more
openalex   +1 more source

Beliefs About Substance Abuse Among Adolescents: What Works? [PDF]

open access: yes, 2014
The purpose of this study was to explore beliefs about what works in substance abuse treatment among adolescents. This was a qualitative study that was comprised of fourteen counselors who were interviewed regarding what works in substance treatment with
Araiza, Stephanie Michelle   +1 more
core  

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

open access: yesAdvanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu   +10 more
wiley   +1 more source

An investigation of scale effects in family substance abuse treatment programs

open access: yesSubstance Abuse Treatment, Prevention, and Policy, 2010
This short report investigates scale effects in family substance abuse treatment programs. In Massachusetts, the family substance abuse treatment programs were much more costly than other adult residential treatment models. State officials were concerned
Lee A James
doaj   +1 more source

BELIEFS ABOUT SUBSTANCE ABUSING CLIENTS AMONG SOCIAL WORK STUDENTS [PDF]

open access: yes, 2014
This study was a quantitative survey and explored beliefs about substance abusing clients among sixty-three social work students. The study focused on the extent to which social work students display bias toward clients with a substance abuse disorder ...
Soto, Seidy Jhosselyn   +1 more
core  

Genetics‐Based Targeting Strategies for Precise Neuromodulation

open access: yesAdvanced Science, EarlyView.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He   +11 more
wiley   +1 more source

Profiles of Childhood Trauma in Women With Substance Use Disorders and Comorbid Posttraumatic Stress Disorders

open access: yesFrontiers in Psychiatry, 2019
Background: It is increasingly becoming accepted that substance use disorders, including substance abuse and substance dependence, are closely related to childhood trauma and posttraumatic stress disorders.
Annett Lotzin   +8 more
doaj   +1 more source

Comorbidities and Race/Ethnicity Among Adults with Stimulant Use Disorders in Residential Treatment [PDF]

open access: yes, 2015
Comorbid physical and mental health problems are associated with poorer substance abuse treatment outcomes; however, little is known about these conditions among stimulant abusers at treatment entry.
Carmody, Thomas   +5 more
core   +1 more source

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