Results 161 to 170 of about 878,624 (401)

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

Advanced Science, EarlyView.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li, Xinran Dong, Kexing Gao, Yiyang Wang, Min Li, Huayun Deng, Shuangyu Ma, Yaping Lv, Wei Jin, Quanfu Li, Yuming Wang, Xiaodong Liao, Kangjing Bian, Aiwu Zhou, Chengping Hu, Lei Huang   +15 more
wiley   +1 more source

Substance Abuse in Addicts Referred to Public and Private Substance Abuse Treatment Centers

International Archives of Health Sciences, 2015
Aims Drug addiction is a mental, social, and economic problem that comes from abnormal and illicit consumption of substances such as alcohol, opium, hashish, and etc., making the addict psychologically and physiologically dependent to those substances.
Kadkhodaei M.* MSc,, Akbari H.1 PhD,, Sokut A.2 MSc   +2 more
doaj  

Perceived Discrimination in Health Care and Mental Health/Substance Abuse Treatment Among Blacks, Latinos, and Whites

Medical Care, 2017
V. Mays, Audrey L. Jones, Ayesha Delany-Brumsey, Courtney N Coles, S. Cochran   +4 more
semanticscholar   +1 more source

Young Family Critical Time Intervention (CTI): Successful Transitions From Homelessness to Stability [PDF]

, 2010
Describes a model for nine-month intensive interventions to help young mothers moving from shelters to stable housing, including mental health and substance abuse treatment, parenting guidance, and family preservation services.

core  

Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy

Advanced Science, EarlyView.
This study introduces a novel transdermal delivery system of molecular hydrogen for postoperative pain relief and wound healing. This system utilizes sustained‐release photothermal microneedles to integrate hydrogen‐releasing nanoparticles and temperature‐responsive microspheres, achieving acid‐responsive hydrogen release and controlled drug release ...
Aining Zhang, Xue Jiang, Bingrui Xiong, Jiayi Chen, Xin Liu, Siyuan Wang, Bofu Li, Mian Peng, Wei Li   +8 more
wiley   +1 more source

Neuropsychological predictors of goal attainment in substance abuse treatment

, 1999
Gordon Teichner
openalex   +2 more sources

Inpatient treatment of the mentally ill substance abuser: Some medicolegal concerns

, 1989
David Mann
openalex   +1 more source

Addiction Recovery Support: Connecting Primary Care Providers and Community Resources [PDF]

, 2017
Addiction to drugs and alcohol is a pervasive problem throughout Vermont and the U.S., and only a fraction of those needing help receive it. The vast majority of admissions to substance abuse treatment programs do not come from healthcare providers, who ...
Meservey, Amber J
core   +1 more source

GHSR‐Foxo1 Signaling in Macrophages Promotes Liver Fibrosis via Inflammatory Response and Hepatic Stellate Cell Activation

Advanced Science, EarlyView.
Macrophage GHSR‐Foxo1 axis regulates CCl4‐induced liver fibrosis by promoting inflammation and TGF‐β1‐mediated HSC activation. GHSR activates PKA‐dependent phosphorylation of Foxo1 at serine 273, promoting macrophage pro‐inflammatory polarization to enhance the production of pro‐inflammatory cytokines that damage hepatocytes, thereby inducing liver ...
Da Mi Kim, Quan Pan, Zeyu Liu, Weiqi Ai, Hye Won Han, Sakhila K. Banu, Robert Y.L. Tsai, Gus A. Wright, Shaodong Guo, Yuxiang Sun   +9 more
wiley   +1 more source

Motivational Interviewing to Enhance Treatment Initiation in Substance Abusers: An Effectiveness Study [PDF]

, 2001
Kathleen M. Carroll, Bryce Libby, Joseph G. Sheehan, Nancy Hyland   +3 more
openalex   +2 more sources