Results 41 to 50 of about 893,182 (400)

Substance Abuse and Public Health: A Multilevel Perspective and Multiple Responses

open access: yesInternational Journal of Environmental Research and Public Health, 2020
Substance abuse has been a thorny public health concern throughout human history. Manifestly, prevention and treatment are the two main strategies commonly adopted to tackle the problem of substance abuse.
T. W. Lo, J. W. Yeung, C. H. Tam
semanticscholar   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Prevalence of Substance Abuse in Patients with Schizophrenia [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2020
Introduction: Substance abuse is a common comorbidity in patients of Schizophrenia. Link between the use of substances and development of psychosis is demonstrated by high prevalence of substance abuse in schizophrenia.
Parisha Narayan Kelkar   +4 more
doaj   +1 more source

Substance abuse treatment: what do we know? an economist's perspective [PDF]

open access: yes, 2003
The substance abuse treatment literature has basically dealt with four important questions: 1) Is treatment effective? 2) Are all programs equally effective? 3) why do programs differ in their effectiveness?
Machado, Matilde P.
core   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

ART adherence changes among patients in community substance use treatment: a preliminary analysis from MACH14

open access: yesAIDS Research and Therapy, 2012
Background Opiate substitution treatment has been associated with better adherence to lifesaving antiretroviral medications, but the impact of other substance abuse treatment on adherence is unknown.
Rosen Marc I   +10 more
doaj   +1 more source

Trends and correlated outcomes in population-level prescription opioid and transdermal fentanyl use in Israel

open access: yesIsrael Journal of Health Policy Research, 2023
Background In the last twenty years, there was a documented increase in prescription opioid procurement in Israel. However, there is still little evidence of the association between opioid procurement rates, health service utilisation in secondary care ...
Barak Shapira   +5 more
doaj   +1 more source

Substance Abuse Treatment and Public Safety [PDF]

open access: yes, 2008
The Substance Abuse Treatment and Public Safety brief found that the sooner substance abuse is treated, the bigger the long-term cost savings and increases in public safety.

core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Component Analysis of the Illegal Handmade Pills and Capsules for Self-Medicating Substance Dependence in Tehran, Iran [PDF]

open access: yesAddiction and Health, 2018
Background: To self-medicate substance dependence, many substance users consume herbal medicines delivered in herbal medicine shops which are prepared through non-standard methods using a variety of different materials.
Hamid Reza Khoddami-Vishteh   +6 more
doaj  

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