The classification of substance and behavioural addictions: A preliminary investigation [PDF]
, 2012 The term addiction has been used to refer to impaired control over substance use for several centuries however recently there has been a shift toward using this term in the context of non-substance use disorders, such as pathological gambling.
McLaughlan, Andre David +1 more
core +1 more source
DeckerMed Medical Cannabis, 2018 There is a consistent body of evidence showing that substance abuse and dependence can worsen preexisting medical conditions, can temporarily mimic medical and psychiatric disorders, and can themselves cause medical problems, including life-threatening overdose.
openaire +1 more source
Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase
FEBS Letters, EarlyView.The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu +5 more
wiley +1 more source
FEBS Letters, EarlyView.The yeast mitoribosome assembly factor Rsm22 contains a [4Fe‐4S] cluster that is matured by the mitochondrial iron–sulfur cluster assembly (ISC) machinery. Defects in ISC components result in impaired mitochondrial protein synthesis due to a mitoribosome assembly defect.
Ulrich Mühlenhoff +4 more
wiley +1 more source
Mental health among northern New Hampshire young adults: depression and substance problems higher than nationwide [PDF]
, 2013 This brief uses data on depressive and substance abuse symptoms from two surveys administered in 2011—the Coös Youth Study and the National Survey on Drug Use and Health—to compare mental health patterns among young adults in Coös County, New Hampshire ...
Van Gundy, Karen T.
core +1 more source
Ch.-H. LEES et G.-D. CHORLTON. — On a simple apparatus for determining the thermal conductivities of cements and other subtances used in the arts (Appareil simple pour déterminer les conductibilités thermiques de ciments et d'autres substances employées dans les arts); Phil. Mag., 5e série, t. XLI, p. 495 ; 1896 [PDF]
, 1896 E. Bouty
openalex +1 more source
Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution
FEBS Letters, EarlyView.The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai +2 more
wiley +1 more source
Harm Reduction JournalBackground Harm reduction (HR) is a critical response to the pronounced toxicity deaths being experienced in Canada. HR providers report many benefits of their jobs, but also encounter chronic stress from structural inequities and exposure to trauma and ...
Sheena Taha +3 more
doaj +1 more source
The use of sandpaper in the preparation of histologic ground sections of hard substances [PDF]
, 1918 J. I. Fanz
openalex +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source