Results 151 to 160 of about 802,297 (310)

Governor's Council on Substance Use Disorder - March 18, 2025

Downloaded from: https://www.nj.gov/gcsud/gcsud/agendas-minutes/ Agenda and minutes are in separate ...
New Jersey. Governor's Council on Substance Use Disorder
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Governor's Council on Substance Use Disorder - June 18, 2024

Downloaded from: https://www.nj.gov/gcsud/gcsud/agendas-minutes/ Agenda and minutes are in separate ...
New Jersey. Governor's Council on Substance Use Disorder
core  

Initial Validation of a Computerized Adaptive Test for Substance Use Disorder Identification in Adolescents

Purpose: Computerized adaptive tests (CATs) are highly efficient assessment tools that couple low patient and clinician time burden with high diagnostic accuracy.
Marriott, Brigid R., Hulvershorn, Leslie A., Smoker, Michael P., Aalsma, Matthew C., Adams, Zachary W., Gibbons, Robert D.   +5 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Governor's Council on Substance Use Disorder - March 19, 2024

Downloaded from: https://www.nj.gov/gcsud/gcsud/agendas-minutes/ Agenda and minutes are in separate ...
New Jersey. Governor's Council on Substance Use Disorder
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Comorbidities of substance use: Opportunities realized and future needs. [PDF]

J Subst Use Addict Treat
Feinberg J, Horigian V, Schmidt R, Feaster D, Metsch L, Hefner K, Shmueli-Blumberg D, Vena A, Hatch M, Ertl MM, Shoptaw S, Haynes L, Brown J, Korthuis PT, Masson C, Del Rio C, Tross S.   +16 more
europepmc   +1 more source

Governor's Council on Substance Use Disorder - October 15, 2024

Downloaded from: https://www.nj.gov/gcsud/gcsud/agendas-minutes/ Agenda and minutes are in separate ...
New Jersey. Governor's Council on Substance Use Disorder
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source