Results 51 to 60 of about 2,088,860 (358)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Receipt of COVID-19 emergency funds and engagement in sex work during COVID-19 among people who use drugs: evidence from Vancouver, Canada

Harm Reduction Journal
Background During the early period of the COVID-19 pandemic, public health orders disrupted income generation in numerous sectors and many governments provided emergency financial support.
Erica McAdam, Kanna Hayashi, Zishan Cui, Haleigh Anderson, Scarlett Nelson, M.-J. Milloy, Kora DeBeck   +6 more
doaj   +1 more source

Doing community-based research during dual public health emergencies (COVID and overdose)

Harm Reduction Journal, 2023
Meaningful engagement and partnerships with people who use drugs are essential to conducting research that is relevant and impactful in supporting desired outcomes of drug consumption as well as reducing drug-related harms of overdose and COVID-19 ...
Phoenix Beck McGreevy, Shawn Wood, Erica Thomson, Charlene Burmeister, Heather Spence, Josh Pelletier, Willow Giesinger, Jenny McDougall, Rebecca McLeod, Abby Hutchison, Kurt Lock, Alexa Norton, Brittany Barker, Karen Urbanoski, Amanda Slaunwhite, Bohdan Nosyk, Bernie Pauly   +16 more
doaj   +1 more source

FoxO1 signaling in B cell malignancies and its therapeutic targeting

FEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac, Petra Pavelkova, Laura Ondrisova, Marek Mraz   +3 more
wiley   +1 more source

Illicit substance use among university students from seven European countries: A comparison of personal and perceived peer use and attitudes towards illicit substance use [PDF]

, 2014
Objective: To compare European students' personal use and approval of illicit substance use with their perceptions of peer behaviours and attitudes, and investigate whether perceptions of peer norms are associated with personal use of illicit substances ...
Ali, Arbour-Nicitopoulos, B. Vriesacker, B.M. Bewick, Berkowitz, Boot, Borsari, Buckner, C. Stock, European Monitoring Centre for Drugs, Drug Addiction (EMCDDA), European Monitoring Centre for Drugs, Drug Addiction (EMCDDA), European Monitoring Centre for Drugs, Drug Addiction (EMCDDA), F. Guillen-Grima, F. Salonna, G. Van Hal, H. Zeeb, Humeniuk, J. McAlaney, Kilmer, Kypri, Larimer, Lintonen, Martens, McAlaney, Neighbors, Neighbors, Page, Perkins, Perkins, Perkins, Perkins, Perkins, Pischke, Prince, R.C. Dempsey, R.T. Mikolajczyk, S.M. Helmer, UN Office on Drugs, Crime (UNODC), Wolfson, Y. Akvardar   +39 more
core   +1 more source

Stimulant safe supply: a potential opportunity to respond to the overdose epidemic

Harm Reduction Journal, 2020
Background Occurring against the backdrop of an overdose crisis, stimulant use and stimulant-involved deaths in North America are increasing at an alarming rate.
Taylor Fleming, Allison Barker, Andrew Ivsins, Sheila Vakharia, Ryan McNeil   +4 more
doaj   +1 more source

Perspectives of HIV-positive and -negative people who use drugs regarding the criminalization of HIV non-disclosure in Canada: a qualitative study

BMC Public Health, 2020
Background While previous research has identified how criminalization of HIV non-disclosure can have deleterious effects on those living with HIV, the perspectives of people who use drugs – a population disproportionately affected by HIV– should be more ...
Cara Ng, Koharu Loulou Chayama, Andrea Krüsi, Will Small, Rod Knight   +4 more
doaj   +1 more source

Substance use risk profiles and associations with early substance use in adolescence [PDF]

Journal of Behavioral Medicine, 2010
We examined whether anxiety sensitivity, hopelessness, sensation seeking, and impulsivity (i.e., revised version of the Substance Use Risk Profile Scale) would be related to the lifetime prevalence and age of onset of alcohol, tobacco, and cannabis use, and to polydrug use in early adolescence.
Malmberg, M., Overbeek, G.J., Monshouwer, K., Lammers, J., Vollebergh, W.A.M., Engels, R.C.M.E.   +5 more
openaire   +4 more sources

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

The association of family and peer factors with tobacco, alcohol, and marijuana use among Chilean adolescents in neighborhood context [PDF]

, 2011
Research on adolescent use of substances has long sought to understand the family factors that may be associated with use of different substances such as alcohol, tobacco and marijuana.
Andrew Grogan-Kaylor, Cristina Bares, Jorge Delva, Pilar Horner, Pilar Horner   +4 more
core   +1 more source