Results 81 to 90 of about 802,297 (310)

mHealth versus face-to-face: study protocol for a randomized trial to test a gender-focused intervention for young African American women at risk for HIV in North Carolina

BMC Public Health, 2018
Background Disparities in the prevalence of HIV persist in the southern United States, and young African American women have a disproportionate burden of HIV as compared with young women of other racial/ethnic backgrounds.
Felicia A. Browne, Wendee M. Wechsberg, Paul N. Kizakevich, William A. Zule, Courtney P. Bonner, Ashton N. Madison, Brittni N. Howard, Leslie B. Turner   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The association betweeen psychopathology and substance use in young people

, 2011
Includes abstract.Includes bibliographical references.The co-occurrence of problematic substance use and non-substance use psychopathology is very common in psychiatry, and is generally referred to as comorbidity.
Saban, Amina
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Fentanyl assisted treatment: a possible role in the opioid overdose epidemic?

Substance Abuse Treatment, Prevention, and Policy, 2019
Background The current opioid overdose epidemic affecting communities across North America is increasingly driven by illicitly manufactured fentanyl and its related analogues.
Geoff Bardwell, Evan Wood, Rupinder Brar
doaj   +1 more source

OTHER TITLE: Governor's Substance Use Disorders Task Force public comments [2018]

, 2018
"August 2018.""The Governor's Substance Use Disorder Task Force posted notice of their interest to receive public comment on August 2, 2018. The task force accepted public comments through August 9, 2018.
Kansas. Governor's Substance Use Disorders Task Force.
core  

Illicit substance use among university students from seven European countries: A comparison of personal and perceived peer use and attitudes towards illicit substance use [PDF]

, 2014
Objective: To compare European students' personal use and approval of illicit substance use with their perceptions of peer behaviours and attitudes, and investigate whether perceptions of peer norms are associated with personal use of illicit substances ...
McAlaney, J., Guillen-Grima, Farncisco, Stock, C., Bewick, B. M., Akvadar, Yldiz, Bewick, Bridgette M, Zeeb, H., Helmer, S.M., Akvardar, Y., Van Hal, G., Guillén Grima, Francisco, McAlaney, John, Mikolajczyk, R.T., Akvardar, Yildiz, Stock, Christiane, Guillen-Grima, F., Vriesacker, B., Vriesacker, Bart, Van Hal, Guido F., Bewick, Bridgette, Salonna, F., Dempsey, R. C., Helmer, Stefanie, Helmer, S. M., Helmer, Stefanie M., Van Hal, Guido, Salonna, Ferdinand, Dempsey, Robert, Mikolajczyk, R. T., Mikolajczyk, Rafael T., Mikolajczyk, Rafael, et al., Zeeb, Hajo   +32 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source