Results 51 to 60 of about 179,854 (236)

Modeling the Health and Economic Impact of Substandard and Falsified Medicines: A Review of Existing Models and Approaches [PDF]

, 2022
Substandard and falsified medicines are harmful to patients, causing prolonged illness, side effects, and preventable deaths. Moreover, they have an impact on the health system and society more broadly by leading to additional care, higher disease burden,
Nwokike, Jude I., Higgins, Colleen R., Ozawa, Sachiko, Phanouvong, Souly   +3 more
core   +1 more source

Quality of medicines in southern Togo: Investigation of antibiotics and of medicines for non-communicable diseases from pharmacies and informal vendors.

PLoS ONE, 2018
Substandard and falsified medicines represent a serious threat for public health and patient safety. Especially in low and middle-income countries, the prevalence of substandard and falsified medicines is reportedly high. However, reliable information on
Simon Schäfermann, Emmanuel Wemakor, Cathrin Hauk, Lutz Heide   +3 more
doaj   +1 more source

General Public and Community Pharmacists Perception on Counterfeit Medicines: A Preliminary Cross-sectional Study in Qatar [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: One major contributing factor to the prevalence of counterfeit medicines in a country is the lack of knowledge and awareness of the society.
Abubakr A Alfadl, Mohamed Izham Mohamed Ibrahim, Fatima A Maraghi, Khadijah S Mohammad   +3 more
doaj   +1 more source

Prevalence of substandard, falsified, unlicensed and unregistered medicine and its associated factors in Africa: a systematic review

Journal of Pharmaceutical Policy and Practice
Background: Substandard, falsified, unlicensed, and unregistered medicines pose significant risks to public health in developed and developing countries. This systematic review provides an overview of the prevalence of substandard, falsified, unlicensed,
Biset Asrade Mekonnen, Muluabay Getie Yizengaw, Minichil Chanie Worku   +2 more
doaj   +1 more source

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury

Advanced Science, EarlyView.
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang, Jihong Jiang, Huanxin Yin, Chunyan Liu, Hongjun Huang, Yan Luo, Minmin Zhu, Qiuyun Wang   +7 more
wiley   +1 more source

Corruption risks in health procurement during the COVID-19 pandemic and anti-corruption, transparency and accountability (ACTA) mechanisms to reduce these risks: a rapid review

Globalization and Health, 2023
Background Health systems are often susceptible to corruption risks. Corruption within health systems has been found to negatively affect the efficacy, safety, and, significantly, equitable distribution of health products.
Kari A. Griffore, Andrea Bowra, Sara J.T. Guilcher, Jillian Kohler   +3 more
doaj   +1 more source

Pharmaceutical Quality and Policy in Nigeria: Stakeholder Perspectives and Validation of the Mobile Authentication Service [PDF]

, 2015
Background Medicines that are of poor quality present a challenge to many countries especially the developing countries. Many interventions against medicines counterfeiting are often not evaluated and qualitative fieldwork to find how stakeholders ...
Ebenezer, CJ
core  

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Substandard and Falsified Medicines, Regulatory Capacity and Public Health: A Narrative Review With a Focus on Africa. [PDF]

Public Health Chall
Weak medicines regulation in Africa enables the circulation of substandard and falsified medicines, undermining treatment outcomes, accelerating antimicrobial resistance and eroding public trust. This narrative review synthesised 38 studies from 2000 to 2025, highlighting regulatory gaps, public health harms and regional disparities.
Vandy A, Samai NO, Abiri OT, Lahai M, Thomas F, Buffa T, Mansaray S, Turay A, Osborne A.   +8 more
europepmc   +2 more sources

Current Standards of Monitoring Models in Healthcare Settings

Advanced Intelligent Discovery, EarlyView.
AI/ML‐enabled medical devices are entering clinical practice faster than monitoring standards mature. This review highlights gaps in postmarket surveillance, limited use of predetermined change‐control plans, and the need for ongoing performance tracking, drift detection, explainability, and workflow‐aware governance to support safer, more reliable ...
Alan Kay, Daljit Takher, Wenting Liu, Emily Wittrup, Gilbert S. Omenn, Kayvan Najarian   +5 more
wiley   +1 more source