Results 81 to 90 of about 1,609,846 (283)
As many democracies face aging populations, concerns about how to serve senior citizens’ policy interests become increasingly important. Despite seniors forming a growing share of the electorate, they often receive limited legislative attention as a ...
Minkung Jung +3 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
This study aims to analyze the criteria for sound mark registration in Indonesia and compare them with the legal framework applicable in the European Union (EU) jurisdiction.
Marina Ramadhani, Moh. Akmal Hijri
doaj +1 more source
Citoyenneté et participation politique en Écosse. La décentralisation : une chance pour les femmes ?
This paper intends to analyse the notion of citizenship through the devolution process and its impact on the political representation and participation of women in the Scottish Parliament, which has from the beginning ensured a better representation of ...
Karine Rivière-De Franco
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Proportional representation review
Includes supplements.Includes supplements.Mode of access: Internet.Organ of the Proportional Representation League (called, 1914-1920, American Proportional Representation League).The Proportional representation review (v. 1-3) was issued in Chicago from
American Proportional Representation League. +1 more
core
Since Nigeria’s return to democratic rule in 1999, women’s representation in the National Assembly has remained disproportionately low despite numerous democratic and gender equality commitments.
EMMANUEL JOSHUA ANAUREYI +1 more
doaj +1 more source
Cet article se propose d’analyser le profil des dirigeants politiques en Grande-Bretagne à partir de leurs caractéristiques socio-économiques et éducatives.
Karine RIVIÈRE-DE FRANCO
doaj +1 more source

