Results 81 to 90 of about 1,976 (165)
Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen +15 more
wiley +1 more source
This article provides an overview of the current state of the art and future improvements in PV technology and explains how changes in the technology and design of individual PV components—at the module level, the balance‐of‐system (BOS) level, or the PV plant level—can affect the reliability, durability, and energy output of a PV system.
Ulrike Jahn +10 more
wiley +1 more source
The studies on strategies for improving restoration times in electrical distribution systems are extensive. They have theoretically explored the application of mathematical models, the implementation of remotely controlled systems, and the use of digital
Carlos Sánchez-Ixta +3 more
doaj +1 more source
Abstract The Guinea Savanna zone of many countries constitutes a critical cashew‐producing area. Despite its importance, data‐driven recommendations on optimal tree spacing remain largely unavailable to farmers in Ghana. This knowledge gap constrains productivity, reduces returns on investment, and affects farmer interest and ultimately the long‐term ...
Sampson Konlan +7 more
wiley +1 more source
Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs
Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri +10 more
wiley +1 more source
Analysis on Green and Low Carbon Technologies for New Power System Substations
[Introduction] Under the vision of carbon peak and carbon neutralization, the construction of the new power system substations is imperative. [Method] To promote the transformation of traditional substations to new power system substations, a full ...
Jingda GU +4 more
doaj +1 more source
This study explores the spatial ecology of green turtles within the Gorgona National Natural Park (GNNP), providing insights into habitat preferences, movement patterns, and conservation implications for this vulnerable species in the Colombian Pacific. Ten green turtles were tracked in the GNNP using satellite telemetry, with tracking duration ranging
Diego F. Amorocho +4 more
wiley +1 more source
Power system protection devices are vulnerable to adversarial samples. We propose a digital twin and reinforcement learning framework. It trains a virtual model within safe operational boundaries, reducing the false operation rate to below 3.5%. The model's inference delay is under 10 ms, meeting real‐time protection requirements.
Wei Zhang +3 more
wiley +1 more source
The analysis made has shown expediency of modernization rather than reconstruction of earth electrodes, after inspection of long operating substations grounding grids, via building a two-level structure.
I.V. Nizhevskiy, V.I. Nizhevskiy
doaj

