Secondary Site Ligand for Integrin αVβ3 Enables Targeted mRNA Delivery
Angewandte Chemie, EarlyView.Non‐orthosteric, low‐affinity ligands for integrin αVβ3, identified by fragment screening, achieve superselective nanoparticle targeting (ακ ≈ 3) of αVβ3‐overexpressing endothelial cells. Unlike traditional arginine–glycine–aspartate decorated particles, these fragment‐functionalized LNPs discriminate cells by receptor density and deliver mRNA to ...
Sebastian Bayer +7 more
wiley +1 more source
In-Depth Theoretical Investigations of Borazine's Aromaticity: Tailoring Electron Delocalization through Substituent Effects. [PDF]
MoleculesTomut AC, Moraru IT, Nemes G.
europepmc +1 more source
Predictive Registry Optimization of Molecular Adsorbates on Solid Surfaces
Angewandte Chemie, EarlyView.Local C–H “spikes” from a π‐conjugated backbone lock into graphene “pockets”. A geometric registry score turns images obtained by scanning tunneling microscopy at the solid/liquid interface into atomic‐scale adsorption models, enabling assignment of surface atropisomers in large π‐conjugated molecules.
David A. Hofmeister +7 more
wiley +1 more source
Angewandte Chemie, EarlyView.Gradually bent perylene bisimides (PBIs) isolate structural distortion as the sole variable and exhibit negligible intersystem crossing, uncovering rapid vibrational dephasing as the dominant driver of internal conversion through excited‐state vibrational landscape reorganization.
Wei Zhang +8 more
wiley +1 more source
Can N-heterocyclic germylenes behave as Lewis acids - is there another side to Meller germylenes?
Open Chemistry, 2008 Kühl Olaf
doaj +1 more source
π‐Enlargement in Porphyrin Macrocycles at Interfaces
Angewandte Chemie, EarlyView.On‐surface synthesis of a 20‐π free‐base expanded porphyrin, by depositing onto a hot Ag(111) substrate an 18‐π free‐base precursor equipped with ‐CF3 functional groups ABSTRACT Porphyrins are essential heteroatomic macrocycles, fundamental to both biological systems and advanced technology.
Ana Barragán +11 more
wiley +1 more source
Elucidating substituent effects in magnetic properties of redox active cobalt complexes and testing them as potential catalysts for HER. [PDF]
RSC AdvSundaresan S +3 more
europepmc +1 more source
Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations
Angewandte Chemie, EarlyView.Mechanochemistry is redefining metal catalysis by controlling catalyst formulation, speciation, and deployment. This Review shows how milling, LAG, RAM, and TSE enable rapid metal‐complex assembly, distinctive catalytic manifolds, and scalable synthesis beyond solution chemistry.
Sourav Behera +2 more
wiley +1 more source
Phosphinoyl-Substituted Ketenyl Anions: Synthesis and Substituent Effects on the Structural Properties. [PDF]
OrganometallicsJörges M +6 more
europepmc +1 more source
Angewandte Chemie, EarlyView.A catalytic network embedding a formal rearrangement enables the first catalytic enantioselective multicomponent reaction (MCR) of sulfur ylides. In the presence of a bulky chiral phosphoric acid, the reaction combines sulfoxonium ylides, aldehydes and thiols, and affords synthetically versatile β‐hydroxy‐α‐sulfanyl carbonyl compounds in ...
Nicolò Santarelli +10 more
wiley +1 more source