Results 91 to 100 of about 13,866 (306)

Optimization model of staffing for aircraft ground handling in the case of personnel substitutability [PDF]

open access: yesJournal of Project Management
The presented article deals with the mathematical modeling of aircraft ground handling on the service apron to utilize ground personnel more efficiently in the case of existing substitutability of workers.
Jakub Cíleček   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Substitutability between Equity REITs and Mortgage REITs [PDF]

open access: yes
This study extends Seck’s (1996) approach to investigate the degree of substitutability between equity real estate investment trusts (EREITs) and mortgage real estate investment trusts (MREITs).
Kevin C.H. Chiang, Ming-Long Lee
core  

Elimination by Substitution

open access: yesJournal of Symbolic Computation
Let $K$ be a field and $P=K[x_1,\dots,x_n]$. The technique of elimination by substitution is based on discovering a coherently $Z=(z_1,\dots,z_s)$-separating tuple of polynomials $(f_1,\dots,f_s)$ in an ideal $I$, i.e., on finding polynomials such that $f_i = z_i - h_i$ with $h_i \in K[X \setminus Z]$.
Martin Kreuzer, Lorenzo Robbiano
openaire   +4 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Dynamics of consumer responses to cultivated meat in future food systems: Mediation, moderation, and heterogeneity, A quantitative structural equation modeling study in Brazil

open access: yesFuture Foods
The growing demand for animal-based protein has intensified environmental, sanitary, and ethical pressures on food systems, fostering the search for sustainable alternatives to conventional meat production.
Ari Melo Mariano   +3 more
doaj   +1 more source

Is chair-CEO generational difference a substitute governance mechanism to debt financing? [PDF]

open access: yesAJAR (Asian Journal of Accounting Research)
Purpose – The purpose of this paper is to examine whether and how chair-chief executive officer (CEO) generational difference is related to debt financing.
Yee Peng Chow
doaj   +1 more source

Delayed Substitutions

open access: yes, 2007
This paper investigates an approach to substitution alternative to the implicit treatment of the $\lambda$-calculus and the explicit treatment of explicit substitution calculi. In this approach, substitutions are delayed (but not executed) explicitly.
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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