Results 121 to 130 of about 59,412 (310)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The Choice of Prices vs. Quantities under Uncertainty [PDF]

open access: yes
This paper analyzes a duopoly model with stochastic demand in which firms first choose their strategy variable and compete afterwards. Contrary to the existing literature, we show that firms do not always choose a quantity which is the variable that ...
Reisinger, Markus, Ressner, Ludwig
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

MEASUREMENT OF SUBSTITUTABILITY BETWEEN U.S. DOMESTIC CATFISH AND IMPORTED FISH [PDF]

open access: yes
This study examines p-interdependence and quantifies q-substitutability between domestic catfish and different species of imported fish in the U.S. fish market.
Kennedy, P. Lynn, Lee, Young-Jae
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

A Model of Competing Gangs in Networks

open access: yesGames
Two groups produce a network good perceived by a third party, such as a police or military institution, as a ‘public bad’, referred to as ‘crime’ for simplicity. These two groups, considered mafias, are assumed to be antagonists, whether they are enemies
Alexis Poindron, Nizar Allouch
doaj   +1 more source

A SHORT SURVEY ON CHAOTIC DYNAMICS IN SOLOW-TYPE GROWTH MODELS [PDF]

open access: yes
In this paper we review some Solow-type growth models, framed is discrete time, which are able to generate complex dynamic behaviour. For these models � put forward by Day (1982, 1983); B�hm and Kaas (2000); and Commendatore (2005) � we show that ...
Cesare PALMISANI
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

"Substituability between Mobile and Fixed Telephones: Evidence and Implications for India" [PDF]

open access: yes
Substitutability between mobile and fixed phones is an important consequence of India's telecom sector's deregulation since 1991. This paper tests for substitutability between mobile and fixed phones, based on a binary logit model and using the household
Muttur Ranganathan Narayana
core  

A theory of stability in many-to-many matching markets [PDF]

open access: yes, 2006
We develop a theory of stability in many-to-many matching markets. We give conditions under which the setwise-stable set, a core-like concept, is nonempty and can be approached through an algorithm. The usual core may be empty.
Echenique, Federico, Oviedo, Jorge
core   +2 more sources

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