Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Dietary Replacement Impacts of Fish Meal With Corn Gluten Meal on the Growth, Feed Utilization, and Biochemical Composition of Juvenile Red Sea Bream (<i>Pagrus major</i>). [PDF]
Aquac NutrKwon TW, Cho SH.
europepmc +1 more source
Do funding sources complement or substitute? Examining the impact of cancer research publications. [PDF]
J Assoc Inf Sci Technol, 2023 Rotolo D, Hopkins M, Grassano N.
europepmc +1 more source
Employee substitutability as a tool to improve the robustness in personnel scheduling [PDF]
, 2017 Ingels, Jonas, Maenhout, Broos
core +2 more sources
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
The genetic lottery goes to school: Better schools compensate for the effects of students' genetic differences. [PDF]
Proc Natl Acad Sci U S ACheesman R +3 more
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Exploring the associations between features from multi-parametric MR images in Glioblastoma using radiomics. [PDF]
BMC Med ImagingXu L, Zhao W, Guo R, Huang X.
europepmc +1 more source
Effects of "Tobacco Free" Language in Warning Labels on Perceptions of Electronic Cigarettes and Nicotine Pouches among Young Adult Men: A Randomized Trial. [PDF]
Subst Use Misuse, 2023 Keller-Hamilton B +5 more
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source