Results 31 to 40 of about 59,412 (310)

Capabilities' Substitutability and the "S" Curve of Export Diversity

open access: yes, 2013
Product diversity, which is highly important in economic systems, has been highlighted by recent studies on international trade. We found an empirical pattern, designated as the "S-shaped curve", that models the relationship between economic size ...
Lei, Hongmei, Zhang, Jiang
core   +1 more source

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan   +6 more
wiley   +1 more source

Contracting for Competitive Supply Chains under Network Externalities and Demand Uncertainty

open access: yesDiscrete Dynamics in Nature and Society, 2016
Based on network externalities and demand uncertainty environment, supply chain competition model is built; we identify the valid mechanism for the alternative range of profit-sharing contracts and also analyze the effect of product substitutability ...
Xiaojing Liu
doaj   +1 more source

Sustainable development management seen through the prism of natural capital preservation imperative

open access: yesBizInfo, 2022
After explaining the content coverage and elementary explanation of the basic dimensions of the paradigm of sustainable development, the concept of sustainability is considered in the light of preserving the total amount of capital in the production ...
Vladimir Kostić   +2 more
doaj   +1 more source

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Equilibrium contract strategies under asymmetric product substitutability

open access: yesMATEC Web of Conferences, 2017
This paper investigates how asymmetric product substitutability affect the equilibrium contract choices as well as the performances of the supply chain players.
Li Baixun, Nan Yaru
doaj   +1 more source

On the Construction of Substitutes

open access: yes, 2018
Gross substitutability is a central concept in Economics and is connected to important notions in Discrete Convex Analysis, Number Theory and the analysis of Greedy algorithms in Computer Science. Many different characterizations are known for this class,
Balkanski, Eric, Leme, Renato Paes
core   +1 more source

Blood substitutes [PDF]

open access: yesCanadian Anaesthetists’ Society Journal, 1975
Substitutes for whole blood include blood fractions such as plasma, serum albumin and other fluids of various kinds which are not derived from blood but are used as plasma volume expanders; these, include the usual crystaloid intravenous solutions.
openaire   +2 more sources

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

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