Results 91 to 100 of about 972,706 (315)

Derivation of the Hicks Elasticity of Substitution from the Input Distance Function [PDF]

open access: yes
The Hicks or direct elasticity of substitution is traditionally derived from the production function. This paper exploits duality theory to present a more general derivation from the input distance function, which is exactly dual to the Shadow Elasticity
Stern, David I.
core  

Logistic planning and drug formularies : considerations for clinically effective drug substitution [PDF]

open access: yes, 2012
PhDDrug substitution is mainly economically not medically-driven; it can benefit healthcare services but does not directly benefit individual patients. Many healthcare providers have been promoting drug substitution in an attempt to contain their costs.
Alameri, Mubarak Nasser Mubarak Zain
core   +1 more source

Generic policy in Bulgaria: a policy of failure or success?

open access: yesBiotechnology & Biotechnological Equipment, 2016
Generic medicines play a key role in managing the financial resources for pharmaceuticals in every country. This study analysed the generic policy legislative framework in Bulgaria with the aim to identify whether the policy implementation can be ...
Assena Stoimenova   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Elasticities of Substitution and Complementarity [PDF]

open access: yes
This paper is a modern synthesis of the more than seventy years of literature on the elasticity of substitution. At times, authors, such as Mundlak, have provided syntheses of the literature but these often seem to be forgotten by later authors and ...
David I. Stern
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Comparing Phonological Processes in Persian-Arabic Bilingual Children and Monolingual Children

open access: yesJournal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Bilingualism is a common phenomenon in many countries which could increase consonant errors in the speech produced by bilingual children. The aim of this study was to evaluate phonological skills such as occurrence proportion, and
Maryam Delphi   +3 more
doaj  

أوجه الشبه والاختلاف بين الإعلال والإبدال والتعويض في القرآن الكريم دراسة تحليلية The similarities and differences between apophony, substitution and compensation in the Holy Qur’an (Analytical study) [PDF]

open access: yesMaǧallaẗ Kulliyyaẗ al-Luġaẗ al-'arabiyyaẗ bi-Assiut
هدف هذا البحث إلى دراسة أوجه التشابه والاختلاف بين الإعلال والإبدال والتعويض في اللغة العربية، وتطبيقها في القرآن الكريم، حيث إنّ الإعلال إبدال حرف بحرف، وهو خاص بحروف العلة الثلاثة: الألف والواو والياء؛ والإبدال جعل مطلق حرف مكان حرف آخر وفي مكانه نفسه،
محمد حمدنا الله رملي
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Currency Substitution in the Transition Economy : A Case of the Czech Republic 1993-2001 [PDF]

open access: yes
Currency substitution appears to be an important issue affecting the design of monetary policy, especially in transition economies. Therefore, this paper strives to analyze the particular relevance of a currency substitution phenomenon for the Czech ...
Melecký Martin, Komárek Luboš
core  

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