Results 111 to 120 of about 972,706 (315)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Distributional Effects of Growth and the Elasticity of Substitution [PDF]

open access: yes
Reforms that promote economic growth have also an impact on the distribution of capital and income. This paper considers the effect of a rise in the elasticity of substitution between capital and labor.
Marianne Saam
core  

Ventajas de incluir la figura de candidato suplente para la elección de gobernador en el Estado de México

open access: yesRevista del Instituto Electoral del Estado de México. Apuntes Electorales, 2015
En este trabajo se describe la figura jurídica de la suplencia, que en la actualidad está reconocida en la legislación mexicana para diversos cargos de elección federal, estatal y municipal; así, los integrantes del ...
Enrique González de la Paz
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Openness To Trade as a Determinant of the Elasticity of Substitution between Capital and Labor [PDF]

open access: yes
Some recent work on economic growth considers the aggregate elasticity of substitution between capital and labor as a measure of economic flexibility. It is thought to depend on technological and institutional determinants.
Marianne Saam
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Currency substitution in Latin America - lessons from the 1990s [PDF]

open access: yes
The authors study how agents in Latin America allocate their balances between dollar-denominated and domestic currency-denominated accounts. They empirically determine the causes of currency substitution, its significance in recent banking crises, and ...
Somuano, Alejandro   +2 more
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Cross-Country Estimation of the Elasticity of Substitution between Labor and Capital in Manufacturing Industries [PDF]

open access: yes
This paper presents a simple methodology to estimate the elasticity of substitution between labor and capital for firms operating in perfectly competitive factor markets with constant-elasticity-of-substitution technologies.
Sebastián Claro
core  

Impact of Irradiation on the Crystallization and Electrical Properties of Bismuth-Based Superconductors at High Temperatures

open access: yesProceedings of the International Conference on Applied Innovations in IT
The superconducting compound Bi₂(x+y)AgₓCdᵧBa₂Ca₂Cu₃O₁₀+δ was studied using the solid-state reaction method at an annealing temperature of 850°C and under a pressure of 8 tons/cm² applied by a hydraulic press in the presence of sufficient oxygen.
Hanen Majeed Rashed   +2 more
doaj   +1 more source

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