Results 131 to 140 of about 972,706 (315)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Choice of the substitution currency in Russia: How to explain the dollar's dominance? [PDF]
The analysis of external economic relations of Russia reveals a paradox: while Europe is the main trade and direct investment partner of Russia, this is far from being the case concerning its currency’s role in Russia's financial activities.
Dorbec, Anna
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Electrophilic substitution at a saturated carbon atom /
, 1973 "All chapters in this volume have been written by M.H. Abraham"--Page vi.Includes bibliographical references and index.The formation and reactions of carbanions -- Mechanisms of electrophilic substitution at saturated carbon -- The unimolecular mechanism,
Bamford, C. H. +2 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Measuring the possibilities of interfuel substitution [PDF]
What are the costs of making consumption of production activities use less-polluting fuels? The author reviews how the fuel mix used by different industries has changed over time and examines 2 techniques for estimating the responsiveness of fuel demand ...
Bacon, Robert
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
ELASTICITY OF SUBSTITUTION BETWEEN LABOUR AND CAPITAL ACROSS TWENTY SIX MAJOR INDUSTRIES IN INDIA DURING 2004-05 [PDF]
The magnitude of the elasticity of substitution between labour and capital across twenty six major Industries [Factory Sector] in India has been estimated in the present paper by fitting a Constant Elasticity of Substitution Production Function for the ...
UPENDER, M.
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Stability analysis in a monetary model with a varying intertemporal elasticity of substitution [PDF]
Models dealing with monetary policy are generally based on microfoundations that characterize the behaviour of representative agents (households and firms).
Gomes, Orlando
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