Results 351 to 360 of about 10,438,012 (377)
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Substrate specificity of neuraminidases
The Histochemical Journal, 1973This presentation is a brief description of neuraminidases and is mainly concerned with the substrate specificity of these enzymes. From the observed great differences in substrate specificity it is clear that we are dealing not with one enzyme called neuraminidase but with a variety of enzymes named neuraminidases.
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Specifying Substrate Specificity
Science Signaling, 2013Distinct intracellular signaling pathways acting on the substrates of a protease could determine which substrates are cleaved.
W. Wong
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Substrate specificity of Streptomyces transglutaminases
Applied Biochemistry and Biotechnology, 2007Transglutaminase (TGase) is a multifunctional enzyme vital for many physiologic processes, such as cell differentiation, tissue regeneration, and plant pathogenicity. The acyl transfer function of the enzyme can activate primary amines and, consequently, attach them onto a peptidyl glutamine, a reaction important for various in vivo and in vitro ...
Alexander Blinkovsky +5 more
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Engineering substrate specificity
Current Opinion in Structural Biology, 1991Site-directed mutagenesis of amino acids in the active site of an enzyme can yield mutant proteins with dramatically altered substrate specificity. In the past year, several enzymes have been successfully engineered with desired changes in specificity.
David A. Agard, Charles B. Wilson
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Substrate specificity of choline kinase
Archives of Biochemistry and Biophysics, 1987The substrate specificity of choline kinase (ATP:choline phosphotransferase, EC 2.7.1.32) from brewer's yeast has been examined using multiple analogs of choline, most of which have been reported to be a substrate of one or another choline-using system from other sources.
Greg L. Clary +2 more
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Substrate specificity for pancreatic amylase
Gastroenterologia Japonica, 1978Substrates commonly used for the determination of amylase activity include potato starch, corn starch and dye-labeled starch. Determination of the amylase activity of serum using these different starches has shown that the measured value varies depending upon the ratio of isoamylases present, namely between pancreatic amylase (P-type) and salivary ...
Tadahiko Kozu +5 more
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Substrate specificity of squalene synthetase
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 198022 artificial homologues of farnesyl pyrophosphate were examined for the reactivity as substrate for squalene synthetase of pig liver microsomes. 16 of the homologues were found to be reactive to give corresponding squalene-like products. Extention of the omega-terminal of the carbon chain of farnesyl pyrophosphate is acceptable to the enzyme at least ...
Seto Shuichi +2 more
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Substrate specificity of pancreatic lipase
Biochimica et Biophysica Acta (BBA) - Enzymology, 1968Abstract 1. 1. The hydrolysis of esters of oleic acid by pancreatic lipase (glycerol-ester hydrolase, EC 3.1.1.3) depends on the nature of the alcohol. Two factors appear to influence the speed of the reaction: an inductive effect, and steric hindrance. 2. 2.
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[37] Substrate docking algorithms and the prediction of substrate specificity
1996Publisher Summary This chapter describes the substrate docking algorithms and the prediction of substrate specificity. The utility of computer-assisted molecular docking for the prediction of cytochrome P450 substrates has been explored. P450cam is used as the model P450 enzyme because several high resolution crystal structures are available for it ...
De Voss, James J. +1 more
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Substrate Specificity of Peroxidase [PDF]
Science, 1955 Britton Chance, R. R. Fergusson
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