Results 361 to 370 of about 10,438,012 (377)
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Substrate specificity of ascorbate oxidase
Biochemical and Biophysical Research Communications, 1976Abstract Ascorbate oxidase oxidizes leuco 2, 6-dichloroindophenol to the blue quinoid dye and produces spectral changes in the UV spectra of certain substituted polyhydric and amino phenols at pH 5.7. The new peaks produced by the addition of enzyme to the dichlorohydroquinones (2,5 and 2,6) and hydroxyhydroquinone correspond to the respective p ...
Charles R. Dawson, Jean Dayan
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Substrate specificity of bleomycin hydrolase
Biochemical Pharmacology, 1989Bleomycin (BLM) hydrolase is believed to protect both malignant and normal tissue from the toxicity of the antitumor drug BLM. Little is known about the substrate specificity of BLM hydrolase. Thus, we developed ion-paired reverse phase high speed liquid chromatography systems to assay for the metabolism of several BLM analogs.
Sidney M. Hecht +4 more
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Substrate specificity of strictosidine synthase
Bioorganic & Medicinal Chemistry Letters, 2006Strictosidine synthase catalyzes a Pictet-Spengler reaction in the first step in the biosynthesis of terpene indole alkaloids to generate strictosidine. The substrate requirements for strictosidine synthase are systematically and quantitatively examined and the enzymatically generated compounds are processed by the second enzyme in this biosynthetic ...
McCoy, E, Galan , MC, O'Connor, SE
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Understanding the substrate specificity of conventional calpains
Biological chemistry, 2012: Calpains are intracellular Ca2+-dependent Cys proteases that play important roles in a wide range of biological phenomena via the limited proteolysis of their substrates.
H. Sorimachi, Hiroshi Mamitsuka, Y. Ono
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Substrate specificity of vertebrate collagenase
Biochimica et Biophysica Acta (BBA) - Enzymology, 1976Substrate specificity of purified tadpole collagenase (EC 3.4.24.3) has been studied using eleven synthetic peptides. A pentapeptide, t-butyloxycarbonylprolylalanylglycylisoleucylalanine amide, was susceptible to the action of the enzyme and an octapeptide, acetylprolylglutaminylglycylisoleucylalanylglycylglutaminylarginine ethyl ester, was proposed to
Yoshihiro Masui +2 more
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Substrate specificity of muscle aldolase
Biochimica et Biophysica Acta, 1954A study of the substrate specificity of rabbit muscle aldolase led to the following observations. 1. 1. Both the d and l isomers of glyceraldehyde-3-phosphate can be condensed with dihydroxylacetone phospahte, but the former appears to react much more rapidly than the latter. 2. 2. Tagatose-i, 6-diphosphate, which possesses a cis configuration
William L. Byrne +3 more
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Computation of enzyme-substrate specificity
Biochemistry, 1981The present study reports the development of a new procedure for teh theoretical computation of enzyme-substrate specificities. The immediate goal has been to identify experimental data with which computations may be effectively compared, examine the underlying theoretical principles, and demonstrate feasibility.
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2003
Matrix metalloproteinases (MMPs) are secreted or cell surface-bound zinc metalloendopeptidases that act on extracellular matrix (ECM) macromolecules. Thus, isolated MMPs have been tested against various components of ECM. Based on similarities in primary structure and the abilities to cleave ECM components, MMPs are grouped into collagenases ...
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Matrix metalloproteinases (MMPs) are secreted or cell surface-bound zinc metalloendopeptidases that act on extracellular matrix (ECM) macromolecules. Thus, isolated MMPs have been tested against various components of ECM. Based on similarities in primary structure and the abilities to cleave ECM components, MMPs are grouped into collagenases ...
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Adhesives for Specific Substrates
2018The service environment is at least as important in the selection of an adhesive as the nature of the surfaces. The characteristics required of an adhesive which must withstand a low static load under ambient temperature and low-humidity conditions are vastly different from those required of a product which must endure large cyclic stresses in a moist,
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