Results 201 to 210 of about 2,340,556 (352)

Substrate specificity of endoglucanase A from Cellulomonas fimi: fundamental differences between endoglucanases and exoglucanases from family 6

, 1996
Howard G. Damude, Vito Ferro, Stephen G. Withers, R. A. J. Warren   +3 more
openalex   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

How enzymes make the right choice during biosynthesis. [PDF]

Elife
Ramírez AS, Perez C.
europepmc   +1 more source

THE GEOMETRIC QUANTUM SUBSTRATE (GQS)

Cory Brent
openalex   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Substrate Fragility and the Mechanics of Ritual, Fear, and Qualia: A Unified MROS Analysis

Djems Mortimer
openalex   +1 more source

OBSERVATIONS ON THE SUBSTRATE SPECIFICITY OF AMINE OXIDASES [PDF]

, 1959
H. Blaschko, T Chruściel
openalex   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

SERS Substrate Fabrication via Rapid Triboelectrification-Driven Self-Assembly of Close-Packed Colloidal Monolayers. [PDF]

Small Methods
Feizpour M, Jimidar ISM, de Waard MTJ, Desmet G, Ottevaere H.   +4 more
europepmc   +1 more source

The Unified Alignment Equation: Coupling Consciousness, Cooperation, and Thermodynamics Across Substrates

FLYNN, OCEAN
openalex   +1 more source