Results 111 to 120 of about 3,555 (297)

Substructuring of a Petrol Engine: Dynamic Characterization and Experimental Validation

open access: yesApplied Sciences, 2019
In this work, the vibration behavior of a 4-cylinder, 4-stroke, petrol engine was simulated by leveraging on the Finite Element Method (FEM). A reduced modelling strategy based on the component mode synthesis (CMS) was adopted to reduce the size of the ...
Enrico Armentani   +4 more
doaj   +1 more source

Revisiting Target‐Aware de novo Molecular Generation with TarPass: Between Rational Design and Texas Sharpshooter

open access: yesAdvanced Science, EarlyView.
TarPass provides a rigorous benchmark for target‐aware de novo molecular generation by jointly evaluating protein‐ligand interactions, molecular plausibility, and drug‐likeness on 18 well‐studied targets. Results show that current models often fail to consistently surpass random baseline in target‐specific enrichment, while post hoc multi‐tier virtual ...
Rui Qin   +11 more
wiley   +1 more source

Improving Inverse Substructuring

open access: yes, 2019
The electrification of drive trains in current and next generation vehicles require vibration dampers that possess different dynamic properties than its internal combustion engine counterparts.
van Haastert, Rutger (author)
core  

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

open access: yesAdvanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu   +15 more
wiley   +1 more source

Landscape genetics reveal broad and fine‐scale population structure due to landscape features and climate history in the northern leopard frog (Rana pipiens) in North Dakota

open access: yesEcology and Evolution, 2019
Prehistoric climate and landscape features play large roles structuring wildlife populations. The amphibians of the northern Great Plains of North America present an opportunity to investigate how these factors affect colonization, migration, and current
Justin M. Waraniak   +4 more
doaj   +1 more source

A Worm‐Inspired Origami Robot with Multimodal Locomotion for Adaptive Mobility in Complex Pipeline Environments

open access: yesAdvanced Science, EarlyView.
An origami worm‐inspired robot achieves multimodal locomotion in confined pipelines through mechatronic integration that embeds actuation, control, and communication within each origami module. Large, reversible configuration and dimensional changes enable 25 gaits synthesized by a unified framework across peristaltic, inchworm, and wheel‐rolling modes
Qiwei Zhang   +6 more
wiley   +1 more source

Hybrid fire testing via the substructuring method

open access: yes, 2017
Originally introduced in the field of earthquake engineering hybrid testing, i.e. the simultaneous combined application of numerical simulation techniques and execution of experiments, is nowadays used in different areas of experimental analysis.
Korzen, Manfred
core  

Decoding Spatial Heterogeneity and Multi‐Omics Regulation with Hierarchical Graph Learning

open access: yesAdvanced Science, EarlyView.
ABSTRACT Recent advances in spatial multi‐omics technologies have enabled the simultaneous profiling of multiple molecular layers within the same tissue slice, providing unprecedented opportunities to investigate tissue spatial organization. However, most existing computational methods identify spatial domains in a purely data‐driven manner, rarely ...
Jiazhou Chen   +6 more
wiley   +1 more source

Stabilizing effect of delay distribution for a class of second-order systems without instantaneous feedback

open access: yes, 2009
In many situations in physics, engineering and biology time delays arise naturally due to the time needed to transport information from one part of the system to another and/or to react to incoming information. When differential equations are used in the
Gabor Kiss   +3 more
core  

Current dynamic substructuring methods as approximations to condensation model reduction

open access: yes, 1994
Condensation Model Reduction (CMR) theory, when viewed as a dynamic substructuring method, is shown to encompass much of the existing dynamic substructuring methods as special cases of a single unified approach.
Flippen, L.D., L.D. Flippen
core   +1 more source

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