Results 91 to 100 of about 676,371 (320)

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Optimising Optimal Image Subtraction

, 2006
Difference imaging is a technique for obtaining precise relative photometry of variable sources in crowded stellar fields and, as such, constitutes a crucial part of the data reduction pipeline in surveys for microlensing events or transiting extrasolar ...
Hessman, Frederic V., Israel, Holger, Schuh, Sonja   +2 more
core   +1 more source

Hypomethylating agents increase L1 retroelement expression without inducing novel insertions in myeloid malignancies

Molecular Oncology, EarlyView.
We investigated whether hypomethylating agents (HMAs) used in myeloid malignancies induce somatic retrotransposition. Our findings indicate that HMA treatment increases L1‐encoded protein expression but does not lead to detectable de novo retrotransposition events in either patient samples or cell lines.
Šárka Pavlová, Hana Svozilová, Marcela Krzyžánková, Radim Sonnek, Anastasiya Volakhava, Anastasia Smirnova, Tatiana Grigoreva, Zuzana Jašková, Hana Synáčková, Dennis Wahl, Michaela Bilčíková, Libor Červinek, Šárka Pospíšilová, Ilgar Mamedov, Karla Plevová   +14 more
wiley   +1 more source

Perturbative subtraction methods [PDF]

Nuclear Physics B - Proceedings Supplements, 2000
Talk presented at LATTICE99(algorithms)
openaire   +3 more sources

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

FEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi, Sara C. Konopka, Thorsten Lang   +2 more
wiley   +1 more source

An analysis of the influence of background subtraction and quenching on jet observables in heavy-ion collisions

, 2012
Subtraction of the large background in reconstruction is a key ingredient in jet studies in high-energy heavy-ion collisions at RHIC and the LHC. Here we address the question to which extent the most commonly used subtraction techniques are able to ...
Apolinário, Liliana, Armesto, Néstor, Cunqueiro, Leticia   +2 more
core   +1 more source

A Comprehensive Survey of Video Datasets for Background Subtraction

IEEE Access, 2019
Background subtraction is an effective method of choice when it comes to detection of moving objects in videos and has been recognized as a breakthrough for the wide range of applications of intelligent video analytics (IVA). In recent years, a number of
Rudrika Kalsotra, Sakshi Arora
semanticscholar   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Progress on NNLO subtraction

, 2006
We review standard subtraction, as a method to compute cross sections at NNLO accuracy.Comment: 6 pages, to appear in the proceedings of the 7th International Symposium on Radiative Corrections (RADCOR05), Shonan Village, Japan ...
Acosta, Anastasiou, Anastasiou, Anastasiou, Anastasiou, Anastasiou, Anastasiou, Anastasiou, Anastasiou, Berends, Bern, Bern, Bern, Bethke, Binoth, Cacciari, Campbell, Catani, Catani, Catani, Del Duca, Dittmar, Frixione, Frixione, Gehrmann-De Ridder, Gehrmann-De Ridder, Gehrmann-De Ridder, Gehrmann-De Ridder, Gehrmann-De Ridder, Gehrmann-De Ridder, Giele, Graudenz, Gábor Somogyi, Hamberg, Hamberg, Harlander, Harlander, Heinrich, Khoze, Kosower, Kosower, Kosower, Moch, Ravindran, Roth, Somogyi, Spira, Vittorio Del Duca, Weinzierl, Weinzierl, Weinzierl, Zoltán Trócsányi   +51 more
core   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source