Bivalent RSVpreF Subunit Vaccine Safety and Immunogenicity in Seropositive 2-<18 Year Olds. [PDF]
Glanternik J +19 more
europepmc +1 more source
New Insights Into Pathogenesis, Diagnostics, and Therapeutic Options for Canine Angiostrongylosis
ABSTRACT Objective To provide a comprehensive overview of Angiostrongylus vasorum infection in dogs, with a particular emphasis on recent developments in the understanding of disease pathophysiology and an update on developments in diagnostic and therapeutic options.
Iris Elgueta +3 more
wiley +1 more source
A Tetravalent Recombinant Subunit Vaccine Provides Protection Against Mixed Challenges with Four <i>Eimeria</i> Species in Chickens. [PDF]
Ma X +9 more
europepmc +1 more source
SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu +5 more
wiley +1 more source
VSA-2-, a novel plant-derived adjuvant for SARS-CoV-2 subunit vaccine. [PDF]
Adam A +8 more
europepmc +1 more source
Mycophenolate mofetil (MMF) is an immunosuppressive drug widely used by solid organ transplant recipients. Although it is known that MMF suppresses immune responses, its exact effects on specific vaccinations have not been investigated yet. Mucosal vaccinations are increasingly used, such as a cholera vaccination consisting of two oral immunizations ...
Boukje C. Eveleens Maarse +4 more
wiley +1 more source
A Trypanothione Synthetase-Based Subunit Vaccine Induces Protective Th1 Immunity against Visceral Leishmaniasis in Mice. [PDF]
Khan E +8 more
europepmc +1 more source
Characterization of carABpyrB operon and role of pyrE in Francisella novicida biofilm
Pyrimidine biosynthesis links metabolism to biofilm regulation in Francisella novicida. During nutrient limitation, reduced pyrimidine availability shifts metabolism from uracil salvage to de novo synthesis, increasing biofilm formation. Mutants in carABpyrB exhibit uracil‐dependent growth defects and elevated biofilm:growth ratios, revealing ...
Katie C. Sprinkel +2 more
wiley +1 more source
CD25 modulation enhances broadly neutralizing antibody response of SARS-CoV-2 subunit vaccine. [PDF]
Li F +8 more
europepmc +1 more source
Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source

