Results 41 to 50 of about 3,686,701 (344)
Journal of Medical Internet Research, 2018 Background eHealth has an enormous potential to improve healthcare cost, effectiveness, and quality of care. However, there seems to be a gap between the foreseen benefits of research and clinical reality.
C. Granja, W. Janssen, M. Johansen
semanticscholar +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Rapid recurrence and radiographic progression of sarcomatoid renal cell carcinoma
Urology Case Reports, 2018 Sarcomatoid renal cell carcinoma (sRCC) is an aggressive variant of renal cell carcinoma (RCC) that has a significantly lower overall survival. Even after prompt surgical extirpation, this histologic variant progresses rapidly.
Mia P. Edelson +3 more
doaj +1 more source
Structural Heart, 2022 Background: Reshaping the dilated left ventricle using a surgically implanted papillary muscle sling has been shown to provide long-term improvement in cardiac function compared to annuloplasty alone in patients with systolic heart failure.
Gregg W. Stone, MD +5 more
doaj +1 more source
Electromechanical Cycle Length Mapping for atrial arrhythmia detection and cardioversion success assessment [PDF]
, 2023 Melina Tourni +6 more
openalex +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Environmental drivers of the resistome across the Baltic Sea
MicrobiomeBackground Antimicrobial resistance is a major global health concern, with the environment playing a key role in its emergence and spread. Understanding the relationships between environmental factors, microbial communities, and resistance mechanisms is ...
Joeselle M. Serrana +4 more
doaj +1 more source
Evolving lipid-based delivery systems in the management of neoplastic disease
Oncology Reviews, 2011 Drug delivery systems for the therapeutic use of cytotoxic chemotherapy are an essential aspect of successful treatment and remain under active evaluation.
Iuliana Shapira +3 more
doaj +1 more source
The Success and Failure of the Schwann Cell Response to Nerve Injury
Frontiers in Cellular Neuroscience, 2019 The remarkable plasticity of Schwann cells allows them to adopt the Remak (non-myelin) and myelin phenotypes, which are specialized to meet the needs of small and large diameter axons, and differ markedly from each other.
K. Jessen, R. Mirsky
semanticscholar +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source