Results 41 to 50 of about 7,596,052 (293)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Rapid recurrence and radiographic progression of sarcomatoid renal cell carcinoma
Urology Case Reports, 2018 Sarcomatoid renal cell carcinoma (sRCC) is an aggressive variant of renal cell carcinoma (RCC) that has a significantly lower overall survival. Even after prompt surgical extirpation, this histologic variant progresses rapidly.
Mia P. Edelson +3 more
doaj +1 more source
Journal of Postsecondary Student Success, 2021 An Introduction to the inaugural issue of the Journal of Postsecondary Student Success by Editor Dr. Shouping Hu.
Shouping Hu
doaj +1 more source
, 2018 Vaccines are considered one of the most important advances in modern medicine and have greatly improved our quality of life by reducing or eliminating many serious infectious diseases. Successful vaccines have been developed against many of the most common human pathogens, and this success has not been dependent upon any one specific class of vaccine ...
Ian J, Amanna, Mark K, Slifka
openaire +2 more sources
Success Through Scripture: Redefining Success from a Biblical Perspective [PDF]
, 2019 The purpose of this thesis is to reveal how an intimate relationship with God can bring internal and external success. The research will demonstrate that success from a relativistic society does not always produce overall success.
Dallas, Bobbi Jo
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Evolving lipid-based delivery systems in the management of neoplastic disease
Oncology Reviews, 2011 Drug delivery systems for the therapeutic use of cytotoxic chemotherapy are an essential aspect of successful treatment and remain under active evaluation.
Iuliana Shapira +3 more
doaj +1 more source
Conceptualising success and failure for social movements [PDF]
, 2009 The paper discusses some of the most significant conceptions of success and failure present in the social movement literature, and highlights the gaps present in these theories.
Saeed, Raza
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Environmental drivers of the resistome across the Baltic Sea
MicrobiomeBackground Antimicrobial resistance is a major global health concern, with the environment playing a key role in its emergence and spread. Understanding the relationships between environmental factors, microbial communities, and resistance mechanisms is ...
Joeselle M. Serrana +4 more
doaj +1 more source