The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Biostratigraphic significance of calcareous dinocysts in the Tithonian of the Pieniny Klippen Belt (southern Poland). [PDF]
Ciurej A, Bąk M, Bąk K, Wolska A.
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Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Comparative Metagenomic Studies Reveal Different Evolutionary Directions of Synthetic Indoor Microbial Communities Under Different Nutritional Conditions. [PDF]
Zhang X, Cai L, Bai Y, Peng F.
europepmc +1 more source
Taxonomic, Phylogenetic and Functional Diversity Behave Differently Under Disturbance Pressure and Complex Land-Use History: Assembly Rules in Grassland Communities. [PDF]
Doni L +7 more
europepmc +1 more source
Enhanced autosuccession after wildfire in a transitional sub-Mediterranean forest ecosystem: evidence from the Kras Plateau (Slovenia). [PDF]
Čarni A +3 more
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Heavy Rain, Less Bloom Under Heat: Succession of Size-Structured Phytoplankton Community Without Biomass Increases in a Monsoonal Korean Coastal Ecosystem. [PDF]
Shin S, Bang D, Lee M, Kang Y.
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Expansion of Ligularia virgaurea patches enhances soil bacterial and fungal diversity in alpine meadows of the Qinghai-Tibet Plateau by mediating soil resource heterogeneity. [PDF]
Song J +6 more
europepmc +1 more source
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The etymology of the word success and its relationship to succession is elucidated. Linkage is made to the consequences of unconscious “legitimate” and “illicit” fulfillments in life. This is explored in the writings of Freud and others. Emphasis is placed on guilt, a major factor blocking the attainment of success.
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